Cholinergic α7 nAChR signaling suppresses SARS-CoV-2 infection and inflammation in lung epithelial cells  

作　　者：Jing Wen Jing Sun Yanhong Tang Jincun Zhao Xiao Su 

机构地区：[1]Unit of Respiratory Infection and Immunity,Institut Pasteur of Shanghai,Chinese Academy of Sciences,Shanghai 200031,China [2]CAS Key Laboratory of Molecular Virology and Immunology,Institut Pasteur of Shanghai,Chinese Academy of Sciences,Shanghai 200031,China [3]University of Chinese Academy of Sciences,Beijing 100049,China [4]State Key Laboratory of Respiratory Disease,National Clinical Research Centre for Respiratory Disease,Guangzhou Institute of Respiratory Health,The First Affiliated Hospital of Guangzhou Medical University,Guangzhou 510120,China

出　　处：《Journal of Molecular Cell Biology》2023年第7期73-76,共4页分子细胞生物学报（英文版）

摘　　要：DearEditor,Coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection,has led to>6 million deaths and posed a huge threat to the global economy and public health.SARS-CoV-2 enters lungepithelial cellsdependingon the binding between SARS-CoV-2 S protein and the host receptor angiotensinconverting enzyme 2(ACE2).

关 键 词：ACE2 LUNG INFECTION 

分 类 号：R373[医药卫生—病原生物学]