牙周细菌光动力疗法在固定正畸治疗青少年患者牙龈炎病变中的应用  

Application of periodontal bacterial photo dynamic therapy in gingivitis lesions in adolescent patients undergo-ing fixed orthodontic treatment

作　　者：陈珊珊 王晓庚[1] CHEN Shan-shan;WANG Xiao-geng(Department of Stomatology,Beijing Anzhen Hospital Affiliated to Capital Medical University,Beijing 100041,China)

机构地区：[1]首都医科大学附属北京安贞医院口腔科,北京100041

出　　处：《临床口腔医学杂志》2024年第5期269-272,共4页Journal of Clinical Stomatology

摘　　要：目的:牙周细菌光动力疗法在接受固定正畸治疗中的应用效果。方法:选取2020年7月~2023年6月接受固定正畸治疗的青少年牙龈炎病变患者80例,随机数表法分为对照组(40例,牙周基础治疗)和研究组(40例,基础治疗+牙周细菌光动力疗法),比较两组菌斑指数(plaque index, PLI)和出血指数(sulcus bleeding index, SBI),探诊出血(bleeding on probing, BOP)阳性点位数和百分率,龈沟液炎症因子水平以及治疗疗效。结果:与治疗前比较,两组治疗2周PLI、SBI,BOP阳性点位数和百分率降低,且与对照组比较,研究组治疗2周PLI、SBI,BOP阳性点位数和百分率更低(P<0.05)。与治疗前比较,两组治疗2周基质金属蛋白酶抑制因子-1(tissue inhibitor of metalloproteinase-1,TIMP-1)升高(P<0.05),基质金属蛋白酶8(matrix metalloproteinase-8,MMP-8)、白细胞介素17(interleukin-17,IL-17)、IL-1β降低,且治疗2周后与对照组比较,研究组血清TIMP-1水平更高,MMP-8、IL-17和IL-1β水平更低(P<0.05)。与对照组治疗总有效率(62.50%)比较,研究组(87.50%)更高(P<0.05)。结论:在接受固定正畸治疗的青少年牙龈炎病变患者开展牙周细菌光动力疗法,可改善PLI、SBI及BOP阳性点位数和百分率,减轻炎症,提高治疗效果。Objective:The application effect of periodontal bacterial photo dynamic therapy in receiving fixed ortho-dontic treatment.Methods:From July 2020 to June 2023,80 adolescent gingivitis patients who received fixed orthodontic treatment were selected and divided into control group(40 cases,initial periodontal therapy)and study group(40 cases,initial periodontal therapy+periodontal bacterial photo dynamic therapy)using a random number table method.The plaque index(PLI)and sulcus bleeding index(SBI),the number and percentage of positive points for bleeding on probing(BOP),inflam-matory factors in gingival crevicular fluid,and treatment efficacy were compared between the two groups.Results:Compared with before treatment,the PLI and SBI,the number and percentage of BOP positive points of the two groups decreased after 2 weeks of treatment,and compared with the control group,the study group had lower PLI and SBI,the number and percentage of BOP positive points after 2 weeks of treatment(P<0.05).Compared with before treatment,the levels of tissue inhibitor of metalloproteinase-1(TIMP-1)increased,while the levels of matrix metalloproteinase-8(MMP-8),interleukin-17(IL-17),and IL-1βdecreased.After 2 weeks of treatment,compared with the control group,the study group had higher levels of serum TIMP-1,lower levels of MMP-8,IL-17 and IL-1β(P<0.05).Compared with the total effective rate of 62.50%in the control group,the study group's 87.50%was higher(P<0.05).Conclusion:Performing periodontal bacterial photo dynamic therapy in adolescent gingivitis patients undergoing fixed orthodontic treatment can improve the number and percentage of positive points for PLI,SBI,and BOP,alleviate inflammation,and improve treatment effectiveness.

关 键 词：牙龈炎 青少年 固定正畸 牙周细菌 光动力疗法 

分 类 号：R781.4[医药卫生—口腔医学] R783.5[医药卫生—临床医学]