线粒体代谢在糖尿病心肌病中的研究进展  

Research progress of mitochondrial metabolism in diabetes cardiomyopathy

作　　者：蔡蕊 商婷婷 周琳 王翠平[1] 袁伟[1] CAI Rui;SHANG Tingting;ZHOU Lin(Department of Cardiology,Affiliated Hospital of Jiangsu University,Zhenjiang 212001,China)

机构地区：[1]江苏大学附属医院心血管内科,镇江212001

出　　处：《中国糖尿病杂志》2024年第4期310-313,共4页Chinese Journal of Diabetes

基　　金：江苏省卫生健康委员会基金项目(H2018004);江苏省青年医学重点人才培养基金项目(QNRC2016837)。

摘　　要：糖尿病心肌病(DCM)是DM心血管并发症,是一种特异性心肌病变,发病机制复杂。心肌线粒体结构和功能障碍是DCM发生发展的核心,线粒体有望成为DCM治疗的新靶点。本文综述线粒体代谢在DCM中的研究进展。Diabetes cardiomyopathy (DCM) is a cardiovascular complication of diabetes mellitus,which is a specific myocardial lesion with complex pathogenesis. The structure abnormalities and dysfunctionof myocardial mitochondria are the core of the development of DCM. Mitochondria are expected to become anew target for DCM treatment. This article reviews the research progress of mitochondrial metabolism inDCM.

关 键 词：糖尿病心肌病 线粒体 能量代谢 

分 类 号：R54[医药卫生—心血管疾病]