枇杷清肺饮加减治疗肺经风热型痤疮48例疗效观察  

Observation on the Therapeutic Effect of Modified Pipa Qingfei Decoction in the Treatment of 48 Acne Cases of Lung Meridian Wind Heat Type

作　　者：李桂云 王雅乐 许苗 曾庆涛 詹群璋 黄海 吴红彦 LI Guiyun;WANG Yale;XU Miao;ZENG Qingtao;ZHAN Qunzhang;HUANG Hai;WU Hongyan(Shenzhen Hospital,Shanghai University of Traditional Chinese Medicine,Shenzhen 518004,China;The First School of Clinical Medicine,Guangzhou University of CM,Guangzhou 510405,China)

机构地区：[1]上海中医药大学深圳医院,广东深圳518004 [2]广州中医药大学第一临床医学院,广州510405

出　　处：《江西中医药大学学报》2024年第3期46-49,共4页Journal of Jiangxi University of Chinese Medicine

基　　金：广东省自然科学基金项目(2020A1515010217);深圳市罗湖区软科学研究计划项目(LX20191212,LX20210101)。

摘　　要：目的:观察枇杷清肺饮加减治疗肺经风热型痤疮的临床疗效。方法:选取2021年7月—2022年11月上海中医药大学深圳医院内分泌科及吴红彦名中医门诊诊治的96例痤疮患者作为观察对象,采取实用型随机对照试验方法,将全部受试者随机分成2组,每组48例。观察组采用口服中药枇杷清肺饮加减治疗,对照组采用口服盐酸多西环素片治疗。比较2组治疗前、治疗6周后痤疮综合分级系统(GAGS)评分及临床疗效,同时进行为期3个月的随访。结果:2组治疗6周后,GAGS评分均有降低,且观察组降低程度更明显,差异有统计学意义(P<0.05);2组总有效率比较,观察组(97.92%)高于对照组(72.92%),差异有统计学意义(P<0.05);2组复发率比较,观察组(10.42%)低于对照组(33.33%),差异有统计学意义(P<0.05)。结论:枇杷清肺饮加减治疗肺经风热型痤疮疗效确切,且复发率低。Objective:To observe the clinical effect of Pipa Qingfei Decoction in treating acne of wind-heat type of lung.Methods:96 acne patients from department of endocrinology of luohu hospital of traditional Chinese medicine of shenzhen city and WU Hongyan outpatient clinic were selected by practical randomized controlled experiment.96 subjects were randomly divided into two groups with 48 cases in each group.Subjects in the treatment group received oral modified pipa Qingfei Decoction,and subjects in the control group received oral doxycycline hydrochloride tablets.The researchers will compare the Comprehensive Acne Grading System(CAGs)scores and clinical outcomes of the two groups of subjects in the 6 weeks before and after GAGS assessment,and will also follow up for 3 months.Results:After 6 weeks of treatment,GAGS score decreased in both groups,and the decrease was more obvious in the treatment group,with a significant difference(P<0.05),indicating that the improvement effect of the treatment group was better.The total effective rate was 97.92%in the treatment group and 72.92%in the control group,and the treatment group was more effective than the control group(P<0.05).The recurrence rate in the treatment group(10.42%)was lower than that in the control group(33.33%).Conclusion:The modified Pipa Qingfei Yin has a definite therapeutic effect on lung meridian wind heat type acne,and has a low recurrence rate.

关 键 词：枇杷清肺饮 痤疮 肺经风热证 痤疮综合分级系统 随机对照试验 

分 类 号：R275.9[医药卫生—中西医结合]