不同开机年龄人工耳蜗植入儿童术后早期语前听能康复效果的研究  

Rehabilitation Effects of Early Prelingual Auditory Development in Children with Different Activation Ages After Cochlear Implantation

作　　者：王芳[1,2] 郑芸 钟萍[1] 王寻懿[1] 顾海玲 尹晓玲 郭兰欣 Wang Fang;Zheng Yun;Zhong Ping;Wang Xunyi;Gu Hailing;Yin Xiaoling;Guo Lanxin(Department of Otolaryngology-Head&Neck Surgery,West China Hospital,Sichuan University,Chengdu 610041,China;The Second Affiliated Hospital of Chengdu Medical College·Nuclear Industry 416 Hospital,Chengdu 610051,China)

机构地区：[1]四川大学华西医院耳鼻咽喉-头颈外科,成都610041 [2]成都医学院第二附属医院·核工业四一六医院,成都610051

出　　处：《成都医学院学报》2024年第3期411-414,共4页Journal of Chengdu Medical College

基　　金：四川省科技厅科技计划项目(No:2020YFS0112);四川大学华西医院成果转化项目(No:311200482)。

摘　　要：目的 探讨不同开机年龄人工耳蜗(CI)植入儿童术后早期语前听能(EPLAD)康复效果,并与健听儿童进行横向比较。方法 选取2015-2022年四川大学华西医院完成CI术后开机的1~4岁听障儿童共141例,按开机年龄分为1~2岁组(n=50)、2~3岁组(n=50)、3~4岁组(n=41)。采用婴幼儿有意义听觉整合量表(ITMAIS)和有意义听觉整合量表(MAIS)进行评估,构建广义估计方程(GEE)模型,分析受试者在开机前和开机后1、3、6、12个月时的EPLAD,并与健听儿童进行比较。结果 141例1~4岁CI植入儿童在开机后各个随访时间点的ITMAIS/MAIS得分均有提高,各个随访时间点量表得分两两比较差异有统计学意义(P<0.05);基于3组不同开机年龄组的ITMAIS/MAIS得分,组间比较差异无统计学意义(P>0.05);3组CI植入患儿在开机12个月内与健听儿童12个月内的得分水平相当。结论 1~4岁CI植入患儿在开机后12个月内,其听能发展水平随着术后康复时间的延长而逐渐提高,EPLAD康复效果与健听儿童一致。不同开机年龄对CI植入患儿术后开机12个月内的ITMAIS/MAIS得分无明显影响。Objective To explore the rehabilitation effects of early prelingual auditory development(EPLAD)in children with different activation ages after cochlear implantation(CI),and to compare the differences in their auditory development with that of normal children.Methods A total of 141 children aged 1 to 4 years who received device activation after CI in West China Hospital of Sichuan University from 2015 to 2022 were selected.They were divided into three groups according to their age of device activation:the 1-2 years old group(n=50),the 2-3 years old group(n=50),and the 3-4 years old group(n=41).The Infant-Toddler Meaningful Auditory Integration Scale(ITMAIS)and Meaningful Auditory Integration Scale(MAIS)were used to assess their auditory ability.The generalized estimating equation(GEE)model was constructed.The EPLAD of the subjects at baseline,and 1,3,6,and 12 months after activation were analyzed and compared with that of normal children.Results The ITMAIS/MAIS scores of the 141 children aged 1 to 4 years with CI were improved with time after activation.Pairwise comparisons of the scale scores at each follow-up time point showed statistically significant differences(P<0.05).There was no significant difference in ITMAIS/MAIS scores among the three groups(P>0.05).The three groups of children with CI had comparable levels of ITMAIS/MAIS scores within 12 months after device activation to those of normal children within 12 months of physiological age.Conclusion For children with CI aged 1 to 4 years,their early auditory ability gradually improved with the extension of rehabilitation time within 12 months after activation.The rehabilitation effects of EPLAD were consistent with that of normal children.Different activation ages have no significant effect on ITMAIS/MAIS scores of CI children within 12 months after activation.

关 键 词：人工耳蜗 儿童 早期语前听能 有意义听觉整合量表 

分 类 号：R764.5[医药卫生—耳鼻咽喉科]