旋转容积调强放疗与静态调强放疗在宫颈癌术后患者剂量学比较研究  

A comparative study of dosimetry between rotational volume modulated radiation therapy and static intensity modulated radiation therapy in postoperative patients with cervical cancer

作　　者：严朝胜 肖捷 李钦 Yan Chaosheng;Xiao Jie;Li Qin(Oncology Division 1,Yangchun People's Hospital,Yangjiang 529600,China;Radiotherapy Area 1,Guangdong Central Hospital of Land Reclamation,Zhanjiang 524002,China)

机构地区：[1]阳春市人民医院肿瘤科一区,阳江529600 [2]广东省农垦中心医院放疗一区,湛江524002

出　　处：《现代仪器与医疗》2024年第2期77-82,共6页Modern Instruments & Medical Treatment

基　　金：湛江市科技计划项目(2019B01251)。

摘　　要：目的比较采用旋转容积调强技术(Volumetric Modulated Arc Therapy,VMAT)和逆向调强放疗技术(Intensity Modulated Radiotherapy,IMRT)两种放疗技术在宫颈癌术后的放疗计划的剂量学差异。方法选取2023年3—9月阳春市人民医院25例术后宫颈癌患者,使用Pinnacle计划系统分别对25例病例进行VMAT和IMRT两种不同技术行放疗计划的制定,对比两种放疗技术的剂量学指标和执行效率指标。结果VMAT计划靶区D_(max)显著小于IMRT计划,而D_(min)、D_(mean)、V_(95)、V_(105)差异无统计学意义,CI和HI差异具有统计学意义。股骨头D_(min),直肠D_(mean)、V_(50)、膀胱V_(50)差异无统计学意义。股骨头D_(max)、D_(mean)、V_(45),直肠V_(40)、V_(30),膀胱D_(mean)、V_(40)、V_(30),小肠D_(max)、V_(30)、V_(20)差异有统计学意义(P<0.05)。VMAT和IMRT技术的MU和治疗时间差异有统计学意义(P<0.05)。VMAT技术MU明显低于IMRT,治疗时间也明显较短(P<0.05)。结论VMAT和IMRT对宫颈癌术后放疗患者均可达到靶区剂量要求和危及器官保护的目的,但其剂量学和执行效率差异明显,可为临床选择放疗方案提供了参考。Objective To compare the dosimetric differences between two radiotherapy techniques,volumetric modulated arc therapy(VMAT)and intensity modulated radiation therapy(IMRT),in the postoperative radiotherapy plan for cervical cancer.Methods From March to September 2023,25 postoperative cervical cancer patients in Yangchun People's Hospital were selected.The Pinnacle planning system was used to develop radiotherapy plans using two different techniques,VMAT and IMRT,respectively.The dosimetric and execution efficiency indicators of the two radiotherapy techniques were compared.Results The target area Dmax of VMAT plan was significantly smaller than that of IMRT plan,while the difference of D_(min),D_(mean),V_(95)and V_(105)was not statistically significant,while the difference of CI and HI was statistically significant.There were no significant differences in femoral head D_(min),rectal D_(mean),V_(50)and bladder V_(50).There were significant differences in D_(max),D_(mean),V_(45)of the femoral head,V_(40),V_(30)of the rectum,D_(mean),V_(40),V_(30)of the bladder,and D_(max),V_(30),V_(20)of the small intestine(P<0.05).There were significant differences in MU and treatment time between VMAT and IMRT(P<0.05).The MU of VMAT was significantly lower than that of IMRT,and the treatment time was also significantly shorter(P<0.05).Conclusion Both VMAT and IMRT can meet the target dose requirements and endanger organ protection in postoperative radiotherapy for cervical cancer patients,but their dosimetry and execution efficiency differ significantly,providing a reference for clinical selection of radiotherapy plans.

关 键 词：Pinnacle系统 宫颈癌放疗 剂量学对比 VMAT IMRT 

分 类 号：TH77[机械工程—仪器科学与技术] R445[机械工程—精密仪器及机械]