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作 者:陈雪梅[1] 王芳[1] 张宏宾[1] 陆红达[1] 唐建梅[1] 蒋建华[1] 徐银[1] CHEN Xuemei;WANG Fang;ZHANG Hongbin;LU Hongda;TANG Jianmei;JIANG Jianhua;XU Yin(Microbial Testing Department of Jiangyin Center for Disease Control and Prevention,Jiangyin,Jiangsu 214431,China)
机构地区:[1]江阴市疾病预防控制中心微生物检验科,江苏江阴214431
出 处:《医学动物防制》2024年第7期657-660,共4页Journal of Medical Pest Control
基 金:江苏省社会组织参与艾滋病防治项目(JS2020-MSM-005)。
摘 要:目的分析江阴市疾病预防控制中心艾滋病(AIDS)自愿咨询检测(voluntary counseling and testing,VCT)门诊咨询者人类免疫缺陷病毒(HIV)的感染情况,为制定艾滋病防控措施提供科学依据。方法对2017—2021年到江阴市疾病预防控制中心(CDC)AIDS VCT门诊咨询人群的血清标本进行HIV抗体检测,并对其个案信息和检测结果进行分析。率的比较采用χ^(2)检验、多变量因素影响采用logistic回归模型进行分析。结果2017—2021年共1092人接受了咨询和检测,检出HIV抗体阳性131例,阳性检出率12.00%;不同年份检测人群的HIV抗体阳性率差异有统计学意义(χ^(2)=18.471,P<0.001);男、女检测比例为3.12∶1,男性HIV抗体阳性率(14.27%)明显高于女性,差异有统计学意义(χ^(2)=16.664,P<0.001);有男男性行为史的咨询者HIV抗体阳性率为32.20%,远高于其他咨询原因的咨询者,差异有统计学意义(χ^(2)=119.070,P<0.001)。多因素logistic回归分析显示,男男同性性行为是HIV感染的高危因素。结论VCT门诊是HIV感染者早发现的重要途径,应通过各种宣传加强对艾滋病高危人群的检测和干预,做到早发现、早治疗,最大限度降低HIV感染者的传播风险。Objective To analyze the Human immunodeficiency virus(HIV)infection status among consultants at the voluntary counseling and testing(VCT)of acquired immunodeficiency syndrome(AIDS)in Jiangyin Center for Disease Control and Prevention(CDC),and to provide a scientific basis for the development of AIDS prevention and control measures.Methods HIV antibody testing was conducted on serum samples of individuals who visited the AIDS VCT clinic for counseling of the Jiangyin CDC from 2017 to 2021,and their case information and test results were analyzed.The comparison of rates was conducted using the Chi-square test,and the multivariate factor impact was analyzed using the logistic regression model.Results From 2017 to 2021,a total of 1092 people received counseling and testing,and a total of 131 HIV antibody positive cases were detected,with a positive detection rate of 12.00%;there was a statistically significant difference in the HIV antibody positivity rate among the population tested in different years(χ^(2)=18.471,P<0.001).The ratio of male to female testing was 3.12∶1,and the HIV antibody positivity rate in males(14.27%)was significantly higher than that in females,with a statistically significant difference(χ^(2)=16.664,P<0.001).The HIV antibody positivity rate of consultants with a history of male-to-male sexual behavior was 32.20%,which was much higher than that of consultants with other counseling reasons,the difference was statistically significant(χ^(2)=119.070,P<0.001).Multivariate logistic regression analysis showed that male homosexual behavior was a high-risk factor for HIV infection.Conclusion VCT clinic is an important way for early detection of HIV-infected persons,and it is necessary to strengthen the detection and intervention of high-risk populations of AIDS through various publicity,so as to achieve early detection and treatment,and minimize the risk of transmission of HIV-infected persons.
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