2011—2022年广州市生殖道沙眼衣原体感染流行特征分析  

Epidemiological characteristics of genital Chlamydia trachomatis infection in Guangzhou from 2011 to 2022

作　　者：何婉苹 王焕丽 汤少开 杨韵青 彭嘉俊 罗权 叶兴东 王建琴 HE Wanping;WANG Huanli;TANG Shaokai;YANG Yunqing;PENG Jiajun;LUO Quan;YE Xingdong;WANG Jianqin(Guangzhou Dermatology Hospital,Guangzhou,Guangdong 510095,China)

机构地区：[1]广州市皮肤病医院,广东广州510095

出　　处：《医学动物防制》2024年第7期661-664,668,共5页Journal of Medical Pest Control

基　　金：广东省科学技术厅2021年民生补助等其它事业性发展支出资金(海外名师)项目(粤科智字[2022]6号);广州市医药卫生科技重大项目(20181A031003);广州市科技计划项目(2024A03J0650)。

摘　　要：目的了解广州市2011—2022年生殖道沙眼衣原体(Chlamydia trachomatis,CT)感染流行特点和发病趋势,为广州市开展CT感染防控提供科学依据。方法通过中国疾病预防控制信息系统收集广州市2011—2022年各医疗机构网络直报的CT感染病例数据,采用Excel 2019软件对数据进行整理,利用Joinpoint 4.9.1.0软件分析CT感染病例发病率的变化趋势。结果2011—2022年广州市累计报告CT感染病例133461例,年均发病率为76.71/10万,发病率呈先升后降的趋势,转折点出现在2018年,2011—2018年以年均5.61%的速率增长(t=4.74,P=0.002),2018—2022年以年均12.92%的速率下降(t=-5.08,P=0.001)。报告病例以女性为主,占77.68%;高发年龄为20~<35岁,占72.59%;职业分布以家务及待业和商业服务人员为主,分别占46.20%和23.56%。从化区、番禺区和花都区年均发病率位居全市前三,发病率分别为170.15/10万、107.51/10万和83.35/10万;番禺区、白云区和海珠区累计报告病例数位居全市前三,分别占18.52%、17.31%和10.60%。结论广州市CT感染疫情居高,受新型冠状病毒感染影响发病率逐年下降明显,但目前尚不能认为未来其发病率将继续呈下降趋势,需进一步观察评估并及时调整防控策略。Objective To understand the epidemiological characteristics and incidence trends of genital Chlamydia trachomatis(CT)infection in Guangzhou from 2011 to 2022,so as to provide a scientific basis for the prevention and control of CT infection.Methods The data of CT infection cases directly reported by the network of medical institutions in Guangzhou from 2011 to 2022 were collected from the China Information System for Disease Control and Prevention.Excel 2019 software was used to organize the data,and Joinpoint 4.9.1.0 software was used to analyze the changing trend of the incidence rate of CT infection cases.Results A total of 133461 cases of CT infection were reported in Guangzhou from 2011 to 2022,with an average annual incidence of 76.71/100000.The incidence rate showed an up-down trend,with the turning point occurring in 2018.From 2011 to 2018 the incidence rate increased with an annual percent change(APC)of 5.61%(t=4.74,P=0.002),and then decreased sharply with an APC of 12.92% from 2018 to 2022(t=-5.08,P=0.001).Most of the reported cases were female and those aged 20-<35 years old,accounting for 77.68% and 72.59% respectively.Occupational distribution was mainly dominated by domestic and non-working and commercial service workers,accounting for 46.20% and 23.56% respectively.The average annual incidence rate of Conghua District,Panyu District and Huadu District were top three in the city,with the incidence rates of 170.15/100000,107.51/100000 and 83.35/100000,respectively.Panyu District,Baiyun District and Haizhu District were top three in terms of cumulative number of reported cases,accounting for 18.52%,17.31% and 10.60%,respectively.Conclusion The epidemic of CT infection is serious in Guangzhou,and the incidence rate of CT infection has decreased significantly year by year due to the influence of COVID-19.However,it is not yet possible to believe that the incidence rate of CT infection will continue its downward trend in the future.Further observation and evaluation are needed to adjust the prevention an

关 键 词：衣原体 性病 病例报告 流行特征 分析 

分 类 号：R759[医药卫生—皮肤病学与性病学] R181.3[医药卫生—临床医学]