妊娠期高血压疾病患者左心室收缩功能及升主动脉弹性的研究  

Left Ventricular Systolic Function and Ascending Aortic Elasticity in Patients with Hypertensive Disorders of Pregnancy

作　　者：王琴 刘罗娜 潘璐 马鑫 Wang Qin;Liu Luona;Pan Lu;Ma Xin(Department of Echocardiography in Heart Center,General Hospital of Ningxia Medical University,Yinchuan 750004,China;Department of Medicine Ultrasound,The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an 710000,China)

机构地区：[1]宁夏医科大学总医院心脏中心功能检查部,银川市750004 [2]西安交通大学第二附属医院医用超声研究室,西安市710000

出　　处：《中国超声医学杂志》2024年第5期541-544,共4页Chinese Journal of Ultrasound in Medicine

基　　金：宁夏自然科学基金项目(No.2023AAC02060、2023AAC03637、2021AAC03320)。

摘　　要：目的应用三维斑点追踪技术(3D-STI)评价妊娠期高血压疾病(HDP)患者左心室收缩功能及升主动脉弹性的改变。方法收集36例HDP患者作为病例组,并收集同期常规产检的20例健康妊娠妇女作为对照组,两组均进行常规超声心动图检查及三维斑点追踪,获取左心室收缩、舒张功能及升主动脉弹性指标,并分析其相关性。结果病例组患者LA、IVSD、LVPWD、LVM、A、a均较对照组高,E/A、e/a、e值均减低,且e/a<1,差异均具有统计学意义(P<0.05);与对照组相比,病例组患者GLS、GRS、GCS均减低,SDI增高,差异均有统计学意义(P<0.05);与对照组相比,病例组患者Ep、ASI均明显增高,AS明显减低,差异均具有统计学意义(P<0.05)。SDI与Ep存在显著正相关性(r=1.000,P<0.05)。结论HDP患者左心室收缩功能降低、不同步指数增高,且不同步指数增高与升主动脉弹性减低相关。Objective To evaluate the changes of left ventricular systolic function and ascending aortic elasticity in patients with hypertensive disorders of pregnancy(HDP)by applying three-dimensional speckle tracking technology(3D-STI).Methods A total of 36 patients with HDP were collected as the case group,and 20 healthy pregnant women who underwent routine obstetric examination during the same period were collected as the control group.Both groups underwent routine echocardiography and 3D-STI to obtain the indexes of left ventricular systolic and diastolic function and ascending aortic elasticity and to analyze their correlation.Results The patients in the case group had higher LA,IVSD,LVPWD,LVM,A and a than those in the control group,and the values of E/A,e/a,and e were all reduced,and e/a<1,with the differences being statistically significant(P<0.05);compared with the control group,the patients in the case group had reduced global longitudinal strain(GLS),global radial strain(GRS)and global circumferential strain(GCS),and increased dyssynchrony index(SDI),with the differences being statistically significant(P<0.05);compared with the control group,the patients in the case group had increased SDI,and the differences were statistically significant(P<0.05);and compared with the control group,the patients in the case group had increased SDI,and the differences were statistically significant.Compared with the control group,patients in the case group had significantly higher Ep,ASI,and lower AS,and the differences were statistically significant(P<0.05).There was a significant positive correlation between SDI and Ep(r=1.000,P<0.05).Conclusions Patients with HDP have reduced left ventricular systolic function,increased SDI,and increased SDI is associated with reduced elasticity of the ascending aorta.

关 键 词：妊娠期高血压疾病 升主动脉弹性 三维斑点追踪技术 

分 类 号：R54[医药卫生—心血管疾病]