婴幼儿肺炎的发生与血清铁蛋白、红细胞参数的相关性探讨  

The correlation between the occurrence of pneumonia and the parameters of serum ferritin and erythrocyte in infants

作　　者：孙龙 贾霞 Sun Long;Jia Xia(Medical Laboratory Center,Ulatqianqi People's Hospital,Bayannur Inner Mongolia,014400,China)

机构地区：[1]乌拉特前旗人民医院医学检验中心,内蒙古巴彦淖尔014400

出　　处：《中外女性健康研究》2024年第6期4-6,34,共4页Women＇s Health Research

摘　　要：目的:探讨与分析婴幼儿肺炎的发生与血清铁蛋白、红细胞参数的相关性。方法:选择2021年1月到2022年12月在本院诊治的婴幼儿肺炎76例作为肺炎组,同期选择本院体检的健康婴幼儿76例作为对照组。检测肺炎组与对照组婴幼儿的血清铁蛋白、红细胞参数,调查婴幼儿的肺功能并进行相关性分析。结果:肺炎组的血清铁蛋白含量显著高于对照组(P<0.05)。肺炎组的呼气峰流速、用力肺活量、第1秒用力呼气量与对照组相比显著偏低(P<0.05)。肺炎组的红细胞分布宽度(RDW)显著高于对照组(P<0.05),红细胞平均体积(MCV)、红细胞平均血红蛋白量(MCH)、红细胞平均血红蛋白浓度(MCHC)等显著低于对照组(P<0.05)。Spearman分析显示肺炎的发生与血清铁蛋白含量、MCHC、MCH、MCV、RDW等存在相关性(P<0.05);二元logistic回归分析显示血清铁蛋白含量、MCHC、MCH、MCV、RDW为导致肺炎发生的重要因素(P<0.05)。结论:婴幼儿肺炎多伴随有血清铁蛋白含量升高与肺功能降低,同时红细胞参数也会出现异常,婴幼儿肺炎的发生与血清铁蛋白、红细胞参数存在相关性。Objective:To explore and analysis the correlation between the occurrence of pneumonia and the parameters of serum ferritin and erythrocyte in infants.Method:76 cases of infant pneumonia treated in our hospital from January 2021 to December 2022 were selected as the pneumonia group,and 76 healthy infants examined in our hospital during the same period were selected as the control group.The serum ferritin and erythrocyte parameters of the infants in the pneumonia group and the control group were detected,and the lung function of the infants was investigated and the correlation was analyzed.Result:The serum ferritin content of pneumonia group was significantly higher than that of control group(P<0.05).The peak expiratory flow rate,forced vital capacity and forced expiratory volume in the first second of the pneumonia group were significantly decreased compared with the control group(P<0.05).The distribution width of red blood cells(RDW)in pneumonia group was significantly higher than that in control group(P<0.05),and the mean volume of red blood cells(MCV),mean hemoglobin content of red blood cells(MCH)and mean hemoglobin concentration of red blood cells(MCHC)were significantly lower than those in control group(P<0.05).Spearman analysis showed that the incidence of pneumonia was correlated with serum ferritin content,MCHC,MCH,MCV,RDW,etc.(P<0.05).Binary logistic regression analysis showed that serum ferritin content,MCHC,MCH,MCV and RDW were important factors leading to pneumonia(P<0.05).Conclusion:Conclusion:Infantile pneumonia is usually accompanied by increased serum ferritin content and decreased lung function,and abnormal erythrocyte parameters.The occurrence of infantile pneumonia is correlated with serum ferritin and erythrocyte parameters.

关 键 词：婴幼儿肺炎 铁蛋白 肺功能 红细胞参数 

分 类 号：R725.6[医药卫生—儿科]