A Skin-Inspired Self-Adaptive System for Temperature Control During Dynamic Wound Healing  

作　　者：Yaqi Geng Guoyin Chen Ran Cao Hongmei Dai Zexu Hu Senlong Yu Le Wang Liping Zhu Hengxue Xiang Meifang Zhu 

机构地区：[1]State Key Laboratory for Modification of Chemical Fibers and Polymer Materials,College of Materials Science and Engineering,Donghua University,2999 North Renmin Road,Shanghai 201620,People’s Republic of China

出　　处：《Nano-Micro Letters》2024年第8期211-224,共14页纳微快报（英文版）

基　　金：financially supported by the National Key Research and Development Program of China(2021YFA1201304/2021YFA1201300);the National Natural Science Foundation of China(52103298).

摘　　要：The thermoregulating function of skin that is capable of maintaining body temperature within a thermostatic state is critical.However,patients suffering from skin damage are struggling with the surrounding scene and situational awareness.Here,we report an interactive self-regulation electronic system by mimicking the human thermos-reception system.The skin-inspired self-adaptive system is composed of two highly sensitive thermistors(thermal-response composite materials),and a low-power temperature control unit(Laserinduced graphene array).The biomimetic skin can realize self-adjusting in the range of 35–42℃,which is around physiological temperature.This thermoregulation system also contributed to skin barrier formation and wound healing.Across wound models,the treatment group healed~10%more rapidly compared with the control group,and showed reduced inflammation,thus enhancing skin tissue regeneration.The skin-inspired self-adaptive system holds substantial promise for nextgeneration robotic and medical devices.

关 键 词：Thermo-reception SELF-REGULATION Flexible electronic system Wound healing 

分 类 号：TP212[自动化与计算机技术—检测技术与自动化装置]