血管内冲击波治疗下肢动脉钙化病变的临床疗效  

Clinical efficacy of intravascular shock wave therapy for lower extremity artery calcification

作　　者：王刚[1] 刘振斌[1] 王博文 李梦虎[1] 雷章成 陆东亚 王娱昕 蒋宜彪 Wang Gang;Liu Zhenbin;Wang Bowen;Li Menghu;Lei Zhangcheng;Lu Dongya;Wang Yuxin;Jiang Yibiao(National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion/Department of Wound and Vascular surgery,First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300381,China)

机构地区：[1]国家中医针灸临床医学研究中心/天津中医药大学第一附属医院疮疡及周围血管外科,天津300381

出　　处：《血管与腔内血管外科杂志》2024年第4期385-388,M0002,共5页Journal of Vascular and Endovascular Surgery

基　　金：2023年度“拓新工程”课题(院2023012);2023年度主题案例项目(ZT-231006331)。

摘　　要：目的探讨血管内冲击波治疗下肢动脉钙化病变的临床疗效及安全性。方法收集2023年1月至2024年1月于国家中医针灸临床医学研究中心/天津中医药大学第一附属医院就诊的60例下肢动脉钙化病变患者的临床资料,所有患者均完成血管内冲击波治疗,比较手术前后所有患者踝肱指数(ABI)、疼痛程度、D-二聚体水平、凝血功能指标,统计手术成功率及术后并发症发生情况。结果术前,ABI为(0.48±0.21),与术后(0.79±0.25)比较,差异有统计学意义(P﹤0.05)。60例患者中45例以疼痛为主要症状,其中,0级疼痛由术前6例增加至术后18例,2级疼痛由术前13例增加至术后17例,4级疼痛由术前15例减少至术后8例,6级疼痛由术前8例减少至术后2例,8级疼痛由术前3例减少至术后0例,无10级疼痛患者。手术前后所有患者凝血功能各项指标、D-二聚体水平比较,差异均无统计学意义(P﹥0.05)。手术成功率为100%,术后均未发生严重夹层、急性血栓等手术并发症。结论血管内冲击波是治疗下肢动脉钙化病变的有效手段,且并发症发生率低,安全、有效。Objective To investigate the clinical efficacy and safety of intravascular shock wave in the treatment of lower extremity artery calcification.Method The clinical data of 60 patients with lower extremity artery calcification who were treated at the National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion/First Teaching Hospital of Tianjin University of Traditional Chinese Medicine from January 2023 to January 2024 were collected.All patients completed intravascular shock wave treatment.The ankle brachial index(ABI),pain degree,D-dimer level,coagulation function indicators of all patients before and after surgery were compared,the success rate of surgery and postoperative complications were counted.Result The preoperative ABI was(0.48±0.21),compared with the postoperative ABI(0.79±0.25),the difference was statistically significant(P<0.05).Among the 60 patients,45 showed pain as the main symptom,among them,grade 0 pain increased from 6 preoperative cases to 18 postoperative cases,grade 2 pain increased from 13 preoperative cases to 17 postoperative cases,grade 4 pain decreased from 15 preoperative cases to 8 postoperative cases,grade 6 pain decreased from 8 preoperative cases to 2 postoperative cases,and grade 8 pain decreased from 3 preoperative cases to 0 postoperative case,there were no patients with grade 10 pain.There were no statistically significant differences in coagulation function indicators and D-dimer levels among all patients before and after surgery(P>0.05).The success rate of the surgery was 100%,and there were no postoperative complications such as severe dissection or acute thrombosis.Conclusion intravascular shock wave is an effective method for treating lower extremity artery calcification,with a low incidence of complications,safety,and effectiveness.

关 键 词：血管内冲击波 下肢动脉钙化病变 临床疗效 

分 类 号：R543[医药卫生—心血管疾病]