CO_(2)点阵激光联合糠酸莫米松乳膏治疗儿童斑秃的效果观察  

Efficacy of Fractional Carbon Dioxide Laser with Mometasone Furoate Cream in the Treatment of Pediatric Alopecia Areata

作　　者：吴龙茂 邱建文 林晓敏 张琪 WU Longmao;QIU Jianwen;LIN Xiaomin;ZHANG Qi(Department of Dermatology,Ganzhou maternal and child health hospital,Ganzhou 331000,China)

机构地区：[1]赣州市妇幼保健院皮肤科,赣州331000

出　　处：《中国医药指南》2024年第17期59-62,共4页Guide of China Medicine

摘　　要：目的探讨CO_(2)点阵激光联合0.1%糠酸莫米松乳膏外用治疗儿童斑秃的临床疗效。方法选取2021年9月至2023年9月将本院皮肤科门诊收治的62例儿童斑秃患者,采用随机数字表法分为对照组及观察组,每组31例。观察组患者给予CO_(2)点阵激光联合0.1%糠酸莫米松乳膏外用治疗,对照组患者仅给予0.1%糠酸莫米松乳膏外用治疗。比较两组患者的治疗效果,观察两组患者不良反应及复发率。结果观察组患儿治疗总有效率为83.87%,高于对照组的58.06%(P<0.05)。治疗后观察组的斑秃面积少于对照组(P<0.05),两组患者治疗后皮肤病学生活质量指数、不良反应及复发率对比均无差异(均P>0.05)。结论CO_(2)点阵激光联合0.1%糠酸莫米松乳膏外用治疗斑秃的临床疗效显著,安全性高。Objective To investigate the clinical efficacy of fractional carbon dioxide(CO_(2))laser combined with 0.1%mometasone furoate cream in the treatment of pediatric alopecia areata.Methods A total of 62 cases of pediatric alopecia areata patients were divided into observation group and control group using random number table method,with 31 cases in each group.Patients in the observation group received treatment with fractional CO_(2)laser combined with topical application of 0.1%mometasone furoate cream,while patients in the control group were treated only with topical 0.1%mometasone furoate cream.The therapeutic effects,adverse reactions,and recurrence rates were compared between the two groups.Results The total effective rate of observation group was 83.87%,which higher than 58.06%of the control group(P<0.05).The area of baldness in the observation group was less than that in the control group after treatment(P<0.05).No significant differences were observed in the modified Children's Dermatology Life Quality Index,adverse reactions and recurrence rates between all the two groups(all P>0.05).Conclusions Combination of fractional CO_(2)laser and 0.1%mometasone furoate cream shows remarkable clinical efficacy for the treatment of alopecia areata with high safety.

关 键 词：斑秃 CO_(2)点阵激光 糠酸莫米松乳膏 儿童 

分 类 号：R758.71[医药卫生—皮肤病学与性病学]