PE孕妇分娩时体质指数联合血浆FIB水平评估产后深静脉血栓栓塞症价值  

Value of the body mass index combined with the plasma fibrinogen level of pregnant women with preeclampsia at delivery for assessing their postpartum deep vein thromboembolism

作　　者：王月 王新彦 刘欣悦 刘春稳 任艳华 徐闻铂 WANG Yue;WANG Xinyan;LIU Xinyue;LIU Chunwen;REN Yanhua;XU Wenbo(Cangzhou Maternal and Child Health Care Hospital,Cangzhou,Hebei Province,061000)

机构地区：[1]河北省沧州市妇幼保健院,061000

出　　处：《中国计划生育学杂志》2024年第6期1393-1396,1401,共5页Chinese Journal of Family Planning

基　　金：沧州市重点研发计划指导项目(222106053)。

摘　　要：目的:探讨子痫前期(PE)孕妇分娩时体质指数(BMI)联合血浆纤维蛋白原(FIB)水平对产后深静脉血栓栓塞症(DVT)的评估价值。方法:回顾性收集本院2021年3月-2022年9月收治的PE孕妇70例临床资料,根据产后是否发生DVT分为DVT组(16例)和非DVT组(54例)。比较两组临床特征,分析影响PE孕妇产后发生DVT的危险因素,分娩时BMI联合血浆FIB水平预测PE孕妇产后发生DVT价值。结果:DVT组妊娠期血栓史、产褥期卧床时间≥72h、分娩时BMI≥30kg/m^(2)占比均大于非DVT组,产前血浆FIB水平(5.3±0.7 g/L)高于非DVT组(4.6±0.6 g/L)(均P<0.05)。有血栓史、产褥期卧床时间>72h、分娩时BMI≥30kg/m^(2)、血浆FIB水平升高为PE患者产后发生DVT的独立危险因素(P<0.05)。分娩时BMI≥30kg/m^(2)、血浆FIB水平以及二者联合预测PE患者产后发生DVT的ROC曲线下面积分别为0.654、0.744、0.836,二者联合预测价值高于单一指标。结论:PE患者分娩时BMI≥30kg/m^(2)、血浆FIB水平高是产后发生DVT的独立危险因素,二项指标联合预测PE孕妇产后发生DVT有一定临床价值。Objective:To investigate the value of body mass index(BMI)combined with the plasma fibrinogen(FIB)level of pregnant women with preeclampsia(PE)at delivery for assessing their postpartum deep vein thromboembolism(DVT).Methods:The clinical data of 70 pregnant women with PE from March 2021 to September 2022 were collected retrospectively.These women were divided into group A(16 women with DVT)and group B(54 without DVT)according to the presence or absence of postpartum DVT of the women.The clinical characteristics of the women were compared between the two groups.The risk factors of the postpartum DVT and the value of the BMI value combined with the plasma FIB level at delivery for predicting the postpartum DVT of the pregnant women with PE were analyzed.Results:The proportions of the pregnancy thrombosis history,the bed rest time during puerperium≥72h and the BMI≥30kg/m^(2) of the women in group A were significantly higher than those of the women in group B,and the FIB level(5.3±0.7 g/L)of the women in group A was significantly higher than that(4.6±0.6 g/L)of the women in group B(all P<0.05).The history of thrombosis,the bed rest time during puerperium>72h,the BMI≥30kg/m^(2),and the increased plasma FIB level of the women with PE were the independent risk factors of their postpartum DVT occurrence(P<0.05).The area under the ROC curve of the BMI≥30kg/m^(2),the plasma FIB level,and the combination of the BMI≥30kg/m^(2) and the plasma FIB level of the women with PE at delivery for predicting postpartum DVT were 0.654,0.744 and 0.836,respectively,and which of the combination of the BMI≥30kg/m^(2) and the plasma FIB level of the women at delivery was significantly higher than that of the BMI≥30kg/m^(2) or the plasma FIB level alone.Conclusion:The BMI≥30kg/m^(2) at delivery and the high plasma FIB level of the pregnant women with PE are the risk factors of their postpartum DVT occurrence,therefore,the combination of the BMI≥30kg/m^(2) and the plasma FIB level of the women at delivery has certain predi

关 键 词：子痫前期 深静脉血栓栓塞 分娩时体质指数 纤维蛋白原 危险因素 预测价值 

分 类 号：R714.6[医药卫生—妇产科学] R543.6[医药卫生—临床医学]