合成生物学领域技术发展态势与研究进展  

Technology Development Trend and Research Progress of Synthetic Biology

作　　者：江洪[1,2,3] 李晓南 高倩 Hong JIANG;Xiaonan LI;Qian GAO(Wuhan Library,Chinese Academy of Sciences,Wuhan 430071,China;Department of Information Resources Management,School of Economics and Management,University of Chinese Academy of Sciences,Beijing 100190,China;Hubei Key Laboratory of Big Data in Science and Technology,Wuhan 430071,China)

机构地区：[1]中国科学院武汉文献情报中心,武汉430071 [2]中国科学院大学经济与管理学院信息资源管理系,北京101408 [3]科技大数据湖北省重点实验室,武汉430071

出　　处：《中国生物工程杂志》2024年第5期118-133,共16页China Biotechnology

基　　金：湖北省软科学研究重点项目(2023EDA019)资助项目。

摘　　要：近年来,合成生物学因其所具有的革命式、颠覆式创新潜力,已经成为世界各国必争的科技战略高地,正在引发新一轮的科技与产业国际竞争。对比分析国内外合成生物学领域的专利发展态势,梳理全球合成生物学在元件工程、线路工程、代谢工程、基因组与细胞工程的基础研究前沿,并对合成生物学在医疗、食品、农业等领域的应用进行归纳。最后针对国家宏观支持、专利技术应用、基础研究发展三个方面提出对我国合成生物学进一步发展的启示与建议。In recent years,due to its revolutionary and disruptive innovation potential,synthetic biology has become a strategic highland for science and technology in all countries of the world,triggering a new round of international competition in science and technology and industry.This paper compares and analyzes the patent development trend in the field of synthetic biology at home and abroad,sorts out the basic research frontiers of global synthetic biology in synthetic biological parts engineering,circuit engineering,metabolic engineering,genome and cell engineering,and summarizes the application of synthetic biology in the fields of medicine,food,agriculture and other fields.Finally,it provides insights and suggestions for the further development of synthetic biology in China from the three aspects of national macro support,patent technology application,and basic research development.

关 键 词：合成生物学 专利分析 元件工程 线路工程 代谢工程 基因组工程 

分 类 号：Q819[生物学—生物工程]