Effect of SARS-CoV-2 infection on semen parameters in sperm bank volunteers with normal sperm concentration  

作　　者：Li Wang Wen-Kai Han Xiao-Hui Song Qi-Lin Zhang An-Quan Guan Yuan Gao Jin-Long Ma 

机构地区：[1]Center for Reproductive Medicine,Shandong University,Jinan 250001,China [2]State Key Laboratory of Reproductive Medicine and Offspring Health,ShandongUniversity,Jinan 250001,China [3]Key Laboratory of Reproductive Endocrinology of Ministry of Education,Shandong University,Jinan 250001,China [4]Shandong KeyLaboratory of Reproductive Medicine,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250001,China [5]Shandong Provincial Clinical Research Center for Reproductive Health,Jinan 250001,China [6]Shandong Technology Innovation Center for Reproductive Health,Jinan 250001,China [7]NationalResearch Center for Assisted Reproductive Technology and Reproductive Genetics,Shandong University,Jinan 250001,China [8]Research Unit of Gametogenesis andHealth of ART-Offspring,Chinese Academy of Medical Sciences(No.2021RU001),Jinan 250001,China

出　　处：《Asian Journal of Andrology》2024年第3期328-332,共5页亚洲男性学杂志（英文版）

基　　金：supported by the National Key Research and Development Program of China(No.2022YFC2703200 and No.2021YFC2700600).

摘　　要：In this study,we aimed to assess the effect of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection on semenparameters.The study comprised 110 sperm volunteers who self-reported SARS-CoV-2 infection from the Human Sperm Bank ofthe Center for Reproductive Medicine,Shandong University(Jinan,China).The volunteers had normal sperm concentration beforeinfection.Each volunteer provided semen samples before and after infection.We selected 90 days after infection as the cutoff point.Semen parameters within 90 days after infection of 109 volunteers(group A)were compared with semen parameters before infection.Moreover,semen parameters on or after 90 days after infection of 36 volunteers(group B)were compared with semen parameters beforeinfection.Furthermore,based on whether the volunteers had completed the three-dose SARS-CoV-2 vaccination booster,volunteersin group A and B were further divided into two subgroups separately.Semen parameters were compared before and after infection ineach subgroup.Our results showed that in this cohort population,the semen quality in volunteers with normal sperm concentrationsbefore infection decreased after SARS-CoV-2 infection within 90 days,while the semen quality returned to preinfection levels after 90days.The completion of a three-dose SARS-CoV-2 vaccination booster may exert a protective effect on semen quality after infection.

关 键 词：SARS-CoV-2 SARS-CoV-2 vaccination semen quality sperm donation sperm parameters 

分 类 号：R698.2[医药卫生—泌尿科学]