维生素D与瘢痕形成相关机制的研究进展  

Advances in the relationship between vitamin D and scar formation

作　　者：李梦婕 陈宁杰[2] 王海涛[1,2] Li Mengjie;Chen Ningjie;Wang Haitao(Second Clinical Medical College,Binzhou Medical University,Yantai 264100,China;Burn and Plastic Surgery Department,Weihai Municipal Hospital Affiliated to Shandong University,Weihai 264200,China)

机构地区：[1]滨州医学院第二临床医学院,烟台264100 [2]山东大学附属威海市立医院烧伤整形科,威海264200

出　　处：《中华整形外科杂志》2024年第5期582-586,共5页Chinese Journal of Plastic Surgery

摘　　要：维生素D作为人体不可或缺的一种微量元素,在多种生物过程中发挥着重要作用。近年来有研究认为维生素D与瘢痕发生发展过程存在相关性,或可成为病理性瘢痕潜在的有效干预药物。该文对维生素D与瘢痕发生发展过程的关系,包括受体通路、生长因子通路、炎症细胞通路等多种机制和途径,以及维生素D在瘢痕治疗上的具体应用进行了综述,旨在为未来进一步探索其在瘢痕治疗领域的作用提供思路。Vitamin D,as an indispensable trace element in the human body,plays an important role in a variety of biological processes.In recent years,studies have suggested that vitamin D is related to the development of scars,and may become a potential effective intervention method for pathological scars.This paper reviewed the relationship between vitamin D and scar formation,including the regulation of receptor pathway,growth factor pathway,inflammatory cell pathway and other mechanisms.Specific applications of vitamin D in scar treatment were also reviewed,aiming to provide ideas for further exploring of its role in the field of scar treatment in the future.

关 键 词：维生素D 瘢痕疙瘩 病理性瘢痕 增生性瘢痕 瘢痕治疗 

分 类 号：R622[医药卫生—整形外科]