2014—2021年镇江市结核分枝杆菌与艾滋病病毒双重感染情况  

Prevalence of Mycobacterium tuberculosis and HIV co-infections in Zhenjiang City from 2014 to 2021

作　　者：戴冰[1] 蒋晖[1] 陈召青 沈经纬[1] 丁厅厅 DAI Bing;JIANG Hui;CHEN Zhao-qing;SHEN Jing-wei;DING Ting-ting(Zhenjiang Municipal Center for Disease Control and Prevention,Zhenjiang Jiangsu 212003,China)

机构地区：[1]镇江市疾病预防控制中心,江苏镇江212003

出　　处：《江苏预防医学》2024年第2期179-181,共3页Jiangsu Journal of Preventive Medicine

摘　　要：目的掌握2014—2021年镇江市结核分枝杆菌(MTB)与HIV双重感染情况,为完善MTB/HIV双重感染防控策略提供依据。方法通过国家结核病管理信息系统和镇江市结核菌/艾滋病病毒双重感染防治管理工作年度报表,收集分析结核病患者与HIV感染者双向筛查及MTB/HIV双重感染患者登记、治疗、转归数据。结果2014—2021年新报告HIV阳性1228例,结核筛查率为99.10%,结核病检出率1.15%(14例);6303例既往报告HIV阳性患者,结核病筛查率99.76%、检出率0.14%(9例)。2014—2021年新报告结核病患者9801例,HIV筛查率为76.78%,HIV阳性检出率为0.07%(5例)。各地区HIV阳性患者结核病筛查率均>98%,结核病患者HIV筛查率均>60%。28例MTB/HIV双重感染患者同时接受抗结核和抗病毒治疗22例(占78.57%),接受单纯艾滋病抗病毒治疗1例(占3.57%),接受单纯抗结核治疗2例(占7.14%),未治疗3例(占10.71%)。24例接受抗结核治疗的双重感染患者中,结核治疗成功19例,成功率为79.17%。结论双向筛查是早期发现MTB/HIV双感患者的重要方法,特别是在新报告的HIV阳性患者中开展结核病筛查,有利于提高MTB/HIV患者的早期发现。Objective To investigate the prevalence of Mycobacterium tuberculosis and HIV co-infections in Zhenjiang City from 2014 to 2021,so as to provide insights into improvements in the control strategy for M.tuberculosis and HIV co-infections.Methods The dual screening of tuberculosis cases and HIV-infected individuals,and the registration,treatment and prognosis of cases with M.tuberculosis and HIV co-infections were collected from National Tuberculosis Management Information System of China and Zhenjiang Municipal annual report tables for management of M.tuberculosis and HIV co-infections and analyzed.Results A total of 1228 newly reported HIV-infected patients were detected in Zhenjiang City from 2014 to 2021,with a tuberculosis screening rate of 99.10%and a tuberculosis detection rate of 1.15%(14 cases),and 6303 previously reported HIV-infected cases were identified,with a tuberculosis screening rate of 99.76%and a tuberculosis detection rate of 0.14%(9 cases).A total of 9801 newly reported tubercu-losis cases were identified in Zhenjiang City from 2014 to 2021,with an HIV screening rate of 76.78%and a positive HIV detection rate of 0.07%(5 cases).The proportion of tuberculosis screening was all>98%among HIV-infected patients across the city,and the percentage of HIV screening was all>60%among tuberculosis patients across the city.Among 28 patients with M.tuberculosis and HIV co-infections,22 cases underwent simultaneously anti-tuberculosis therapy and antiretroviral treatment(78.57%),one case receiving antiretroviral treatment alone(3.57%),2 cases undergoing anti-tuberculosis therapy(7.14%)and 3 cases untreated(10.71%).Of 24 patients with M.tuberculosis and HIV co-infections that underwent anti-tuberculosis therapy,19 cases received successful anti-tuber-culosis therapy,with a success rate of 79.17%.Conclusions Dual screening is an important approach for early identification of M.tu-berculosis and HIV co-infections.Notably,screening of tuberculosis among newly reported HIV-infected individuals facilitates early id

关 键 词：结核病 HIV感染 筛查 双重感染 

分 类 号：R521[医药卫生—内科学] R512.91[医药卫生—临床医学]