气体调控的高分子自组装  

Gas-regulated Polymer Self-assembly

作　　者：牟桂芳 杨翠琴 闫强 Gui-fang Mu;Cui-qin Yang;Qiang Yan(State Key Lab of Molecular Engineering of Polymers,Department of Macromolecular Science,Fudan University,Shanghai 200433)

机构地区：[1]复旦大学,聚合物分子工程国家重点实验室,高分子科学系,上海200433

出　　处：《高分子学报》2024年第7期781-801,共21页Acta Polymerica Sinica

基　　金：国家自然科学基金(基金号22371053,21674022,51703034)资助项目。

摘　　要：响应性高分子是智能高分子的重要组成部分,其可以感应外部刺激、通过改变高分子结构实现对高分子功能的精确调控.气体作为一种不同于常规物理或化学信号的“绿色”刺激方式,用于对高分子自组装过程的调控具有重要意义.然而,由于气体分子通常缺乏可控反应位点且调控过程难以量化控制,目前这一刺激-调控方式的发展相对缓慢.面对上述挑战,本文系统介绍了“气敏高分子”与“气筑高分子”两类新型气体调控的高分子组装系统.结合本课题组工作,总结了以生命体三大气体信号分子——硫化氢(H_(2)S)、一氧化碳(CO)和一氧化氮(NO)为刺激源,面向气敏高分子的设计与可控组装方面的研究进展;以及通过气体动态化学,以二氧化碳(CO_(2))等气体为连接单元,面向气筑高分子的结构设计、动态自组装及其功能应用方面的研究工作.Polymer self-assembly is an important branch of the self-assembly field,and research on the precise control of its assembly process and function is necessary to further broaden its application scope.Gas,as a“green”stimulus,different from conventional physical or chemical signals,is of great significance for the regulation of the self-assembly process of polymers.Combining the work of our research group,this paper systematically introduces two types of new gas-regulated polymer assembly systems:“gas-responsive polymers”and“gas-constructed polymers”.Gas-responsive polymers can respond to external gas signal stimulation,change their amphiphilicity or aggregation state by reacting with gas molecules and specific chemical moieties in the polymer,thereby affecting their self-assembly behavior and outputting functions.The progress of research on the design and controllable assembly of gas-sensitive polymers is summarized,focusing on the three major gas signal molecules in living organisms—hydrogen sulfide(H_(2)S),carbon monoxide(CO),and nitric oxide(NO)as stimuli sources.Gas-constructed polymers use gas molecules as assembly units to construct polymer materials.Then introduces the“dynamic gas bridge”formed between boron/phosphorus frustrated Lewis acid-base pairs and gas molecules such as carbon dioxide(CO_(2)),as well as research on the structure design,dynamic self-assembly,and functional applications of gas-constructed polymers.Finally,the future development of these two types of gas regulated polymers was discussed.Gas-responsive polymers can be used in the design of multi-signal moleculeprogrammed responsive systems,achieving intelligent intracellular targeted release and carrier transport functions.Gas-constructed polymers,while having universality for a broad spectrum of gas molecules,lack selectivity for single gas molecules and have poor chemical tolerance in the design of complex functions.The solution to this problem will lay the foundation for the development of a wider range of functional

关 键 词：高分子自组装 气体 气敏高分子 气筑高分子 功能组装体 

分 类 号：O631[理学—高分子化学]