Metal-Free Synthesis of 2-Aminobenzothiazoles via I2-Catalyzed Tandem Cyclization Reaction of Amines and Carbon Disulfide  

作　　者：Ting Chen Wei Feng Ruitong Yang Shanping Chen Guo-Jun Deng 

机构地区：[1]Key Laboratory for Green Organic Synthesis and Application of Hunan Province,Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education,College of Chemistry,Xiangtan University,Xiangtan,Hunan,411105 China [2]School of Chemistry and Chemical Engineering,Henan Normal University,Xinxiang,Hunan,453007 China

出　　处：《Chinese Journal of Chemistry》2024年第8期846-852,共7页中国化学（英文版）

基　　金：Financial support from the National Natural Science Foundation of China(Nos.22271244,22201240,and 21871226);the Hunan Provincial Natural Science Foundation of China(No.2020JJ5531);Open Research Fund of School of Chemistry and Chemical Engineering,Henan Normal University(2022C02);the Undergraduate Investigated Study and Innovated Experiment Plan from Ministry of Education of China and the Science and Technology Innovation Program of Hunan Province(2020RC1009)is gratefully acknowledged.

摘　　要：Comprehensive Summary,A convenient approach for the construction of 2-aminobenzothiazoles via I2-catalyzed tandem cyclization reaction of amines and carbon disulfide has been developed.The present approach starts from simple and readily available starting materials,affording a series of 2-aminobenzothiazoles in up to 89%yields under metal-free conditions.In this work,C—H/N—H functionalization was achieved and multiple C-hetero bonds were successfully constructed in one pot.

关 键 词：Sulfur heterocycles C-H functionalization CYCLIZATION Tandem reaction Transition-metal-free AMINES lodine N-Heterocycles 

分 类 号：O62[理学—有机化学]