循环式单面光疗与间断式单面光疗对新生儿高胆红素血症血清胆红素水平的影响比较  

Comparison of the effect of cyclic single-sided phototherapy and intermittent single-sided phototherapy on serum bilirubin level in neonatal hyperbilirubinemia

作　　者：梁绮 LIANG Qi(Department of Pediatrics,Guangzhou Conghua District Maternal and Child Health Hospital,Guangdong Province,Guangzhou 510000,China)

机构地区：[1]广州市从化区妇幼保健院儿科,广东广州510000

出　　处：《妇儿健康导刊》2024年第11期50-53,共4页JOURNAL OF WOMEN AND CHILDREN'S HEALTH GUIDE

摘　　要：目的比较循环式单面光疗与间断式单面光疗对新生儿高胆红素血症(NHB)血清胆红素(SB)水平的影响。方法选取2021年1月至2023年1月广州市从化区妇幼保健院收治的93例高胆红素血症新生儿,按照随机数字表法分为对照组(47例)与观察组(46例)。对照组采用间断式单面光疗,观察组采用循环式单面光疗。比较两组临床疗效、黄疸消退时间、胎便初排时间、SB水平、经皮胆红素(TCB)水平及不良反应发生情况。结果两组治疗总有效率比较,差异无统计学意义(P>0.05)。两组黄疸消退时间及胎便初排时间比较,差异无统计学意义(P>0.05)。治疗后,两组SB及TCB水平均较治疗前降低(P<0.05),但两组SB及TCB水平比较,差异无统计学意义(P>0.05)。观察组不良反应总发生率低于对照组(P<0.05)。结论循环式单面光疗与间断式单面光疗治疗NHB的临床效果相当,可有效降低SB及TCB水平,加速黄疸消退及胎便初排,但循环式单面光疗的不良反应总发生率更低。Objective To compare the effect of cyclic single-sided phototherapy and intermittent single-sided phototherapy on serum bilirubin(SB)level in neonatal hyperbilirubinemia(NHB).Methods A total of 93 neonates with hyperbilirubinemia admitted to Guangzhou Conghua District Maternal and Child Health Hospital from January 2021 to January 2023 were selected and divided into the control group(47 cases)and the observation group(46 cases)according to the random number table method.The control group was treated with intermittent single-sided phototherapy,and the observation group was treated with cyclic single-sided phototherapy.The clinical efficacy,jaundice resolution time,fetal stool initial discharge time,SB level,transcutaneous bilirubin(TCB)level,and the occurrence of adverse reactions were compared between the two groups.Results There was no significant difference in the total effective rate between the two groups(P>0.05).There was no significant difference in the time of jaundice resolution and the time of fetal stool initial discharge between the two groups(P>0.05).After treatment,the levels of SB and TCB in both groups were lower than those before treatment(P<0.05),but there were no significant differences in the levels of SB and TCB between the two groups(P>0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05).Conclusion The clinical effect of cyclic single-sided phototherapy is similar to that of intermittent single-sided phototherapy in the treatment of NHB,which can effectively reduce the levels of SB and TCB,accelerate the resolution of jaundice and the initial discharge of fetal stool,but the total incidence of adverse reactions of cyclic single-sided phototherapy is lower.

关 键 词：新生儿高胆红素血症 循环式单面光疗 间断式单面光疗 血清胆红素 经皮胆红素 黄疸消退时间 胎便初排时间 不良反应 

分 类 号：R722.1[医药卫生—儿科]