深圳市新型冠状病毒感染者维生素D水平分析  

Analysis of the Level of Vitamin D in Patients with COVID-19 in Shenzhen

作　　者：杨信尊 殷颂平 吕卉 李瑜 谢雯霓[1] YANG Xinzun;YIN Songping;LYU Hui;LI Yu;XIE Wenni(Shenzhen Third People’s Hospital,Guangdong Shenzhen 518100)

机构地区：[1]深圳市第三人民医院,广东深圳518100

出　　处：《深圳中西医结合杂志》2024年第8期6-8,共3页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

基　　金：深圳市高水平医院建设专项经费资助(深圳市第三人民医院院级课题)(G2022034)。

摘　　要：目的:了解深圳市第三人民医院,即深圳市新型冠状肺炎定点救治医院收治的新型冠状病毒感染者维生素D的营养情况。方法:测定2021年12月13日至2022年2月25日因感染新型冠状病毒而入住深圳市第三人民医院患者的血清25羟基维生素D[25(OH)D]水平,比较不同年龄、性别人群25(OH)D营养水平,并与广东地区体检者进行比较。结果:深圳市新型冠状病毒感染者的25(OH)D水平男女之间比较,差异无统计学意义(P>0.05);<30岁年龄段患者的25(OH)D水平最低,40~49岁年龄段患者的25(OH)D水平最高,组间差异有统计学意义(P<0.05)。深圳市新型冠状病毒感染者的血清25(OH)D平均水平为(54.13±14.80)nmol·L^(-1),较广东地区体检者低,差异具有统计学意义(P<0.05),且新型冠状病毒感染者的维生素D充足率(8.7%)低于体检人群(25.9%),差异具有统计学意义(P<0.05)。结论:深圳市新型冠状病毒感染者的维生素D水平普遍较低,低于广东地区体检人群水平,缺乏和不足人数众多,尤其<30岁年龄段者缺乏较严重,维生素D水平与新型冠状病毒感染可能存在相关性,考虑维生素D与健康有多种相关性,适当提高维生素D水平可能对健康有意义。Objective To analyse the level of vitamin D in patients with coronavirus disease 2019(COVID-19)in Shenzhen Third People's Hospital.The hospital is the designated medical institution forpatients with COVID-19 in Shenzhen.Methods Serum level of 25-hydroxyvitamin D[25(OH)D]was measured in patients with COVID-19 from 13 December 2021 to 25 February 2022.The patients were admitted to Shenzhen Third People's Hospital with COVID-19.Their level of 25(OH)D was compared between different age and gender groups,and with those of the population who underwent a physical examination in Guangdong province.Results There was no statistically significant difference in the level of 25(OH)D between men and women of COVID-19 in Shenzhen(P>0.05).The level of 25(OH)D in the age group<30 years was the lowest,and the level of 25(OH)D in the age group 40-49 years was the highest.There was a statistically significant difference between the groups(P<0.05).The average serum level of 25(OH)D patients with COVID-19 in Shenzhen was(54.13±14.80)nmol·L^(-1),which was lowerthan that of people with physical examination in Guangdong,with a statistically significant difference(P<0.05).And the vitamin D adequacy rate of COVID-19 people(8.7%)was lowerthan that of the people who were examined(25.9%),with a statistically significant difference(P<0.05).Conclusion The level of vitamin D in people with COVID-19 in Shenzhen were generally low,and lowerthan the level of the physical examination population in Guangdong,with a large numbeRof deficiencies and insufficiencies,especially in the<30 years old age group.There is a possibility that the level of vitamin may be correlated with the incidence of COVID-19.Considering that vitamin D has multiple correlations with health,appropriately increasing the level of vitamin D maybe have a positive effect on health.

关 键 词：新型冠状病毒感染 维生素D 体检人群 

分 类 号：R563.1[医药卫生—呼吸系统]