甘精/速效胰岛素对危重症合并糖尿病患者的血糖水平及抢救效率的影响  

Effect of Glargine/Rapid-acting Insulin on Blood Glucose Levels and Resuscitation Efficiency in Critically Ill Combined Diabetes Mellitus Patients

作　　者：叶华福 李杨杨 李宇杨 吴林秀 YE Huafu;LI Yangyang;LI Yuyang;WU Linxiu(Department of Critical Care Medicine,Fujian Zhouning County Hospital,Ningde,Fujian Province,355400 China)

机构地区：[1]福建省周宁县医院重症医学科,福建宁德355400

出　　处：《糖尿病新世界》2024年第7期93-96,共4页Diabetes New World Magazine

摘　　要：目的分析在危重症合并糖尿病患者中采用甘精胰岛素与速效胰岛素对血糖水平及抢救效率的影响。方法选取2021年4月—2023年4月福建省周宁县医院收治的80例危重症合并糖尿病患者为研究对象,采用随机数表法将其分成对照组(40例,采用速效胰岛素治疗)和观察组(40例,采用甘精胰岛素治疗)。对比两组抢救成功率、血糖水平、胰岛功能。结果观察组抢救成功率(95.00%)高于对照组(87.50%),但差异无统计学意义(χ^(2)=1.409,P>0.05)。治疗后,观察组空腹血糖、糖化血红蛋白、血糖变异系数、胰岛素抵抗指数低于对照组,空腹胰岛素高于对照组,差异有统计学意义(P均<0.05)。结论在危重症合并糖尿病患者中采用甘精胰岛素与速效胰岛素均有一定效果,但甘精胰岛素对患者血糖与胰岛功能的改善效果更为显著,更有利于优化预后水平。Objective To analyze the effects of glargine insulin versus rapid-acting insulin on blood glucose levels and resuscitation efficiency in critically ill patients with diabetes mellitus.Methods A total of 80 cases of critically ill patients with diabetes mellitus admitted to Fujian Zhouning County Hospital between April 2021 and April 2023 were selected as the study objects,and were divided into the control group(40 cases,treated with rapid-acting insulin)and the observation group(40 cases,treated with glargine insulin)by the random number table method.Resuscitation suc-cess rate,blood glucose level,pancreatic islet function of the two groups were compared.Results The resuscitation success rate in the observation group was 95.00%higher than that in the control group 87.50%,but the difference was not statistically significant(χ^(2)=1.409,P>0.05).After treatment,fasting blood glucose,glycated hemoglobin A1c,coeffi-cient of variation and homeostatic model assessment of insulin resistance were lower,fasting insulin was higher in the observation group compared with the control group,and the differences were statistically significant(all P<0.05).Conclusion The use of glargine insulin and rapid-acting insulin in critically ill patients with diabetes mellitus both have certain salvage effect,but the improvement effect of glargine insulin on patients'blood glucose and islet condi-tion is more significant,more conducive to optimize prognosis.

关 键 词：甘精胰岛素 速效胰岛素 危重症 糖尿病 血糖水平 抢救效率 

分 类 号：R587.1[医药卫生—内分泌]