植物提取物抑制肾草酸钙结石形成的研究进展  

Research progress in the inhibition of calcium oxalate stone formation by plant extracts

作　　者：刘伟锋[1] 陈文哲[1] 曾国华[1] Liu Weifeng;Chen Wenzhe;Zeng Guohua(Department of Urology,The First Affiliated Hospital of Guangzhou Medical University,Guangdong Provincial Key Laboratory of Urology,Guangzhou 510230,China)

机构地区：[1]广州医科大学附属第一医院泌尿外科、广东省泌尿外科重点实验室,广州510230

出　　处：《中华泌尿外科杂志》2024年第5期405-408,共4页Chinese Journal of Urology

基　　金：国家自然科学基金(82070721);广州市科技计划项目(202102010228)。

摘　　要：肾结石是最常见的泌尿系统疾病,其中以草酸钙结石最为常见。目前草酸钙结石的药物治疗存在依从性差、不良反应多等问题。近年来植物提取物在抑制肾草酸钙结石方面展现出巨大的潜力。本文分别介绍了多糖、多酚、生物碱、黄酮类、有机酸等植物提取物在抑制草酸钙结石中的作用,为临床防治草酸钙结石提供理论依据.Kidney stones is the most common urinary system disease,among which calcium oxalate stones are the most common.The pharmacological treatment of calcium oxalate stones currently in use is associated with low compliance and a high incidence of adverse reactions.In recent years,plant extracts have demonstrated considerable potential in inhibiting renal calcium oxalate stones.This article introduces the role of plant extracts,including polysaccharides,polyphenols,alkaloids,flavonoids and organic acids,in the inhibition of calcium oxalate stones.It also provides a theoretical basis for the clinical prevention and treatment of calcium oxalate stones.

关 键 词：肾结石 草酸钙结石 植物提取物 治疗 预防 

分 类 号：R692.4[医药卫生—泌尿科学]