心外膜脂肪组织体积与频发室性早搏的关系  

Relationship between Epicardial Adipose Tissue Volume and Frequent Premature Ventricular Complexes

作　　者：任丽臣 王喆 郭和合 张永高[1] REN Lichen;WANG Zhe;GUO Hehe(Department of Radiology,the First Affiliated Hospital of ZhengZhou University,Zhengzhou,Henan Province 450052,P.R.China)

机构地区：[1]郑州大学第一附属医院放射科,450052 [2]郑州大学第一附属医院心内科,450052

出　　处：《临床放射学杂志》2024年第5期741-745,共5页Journal of Clinical Radiology

基　　金：河南省医学科技攻关省部共建重点项目(编号:SBGJ202102113)。

摘　　要：目的 探究心外膜脂肪组织(EAT)体积与频发室性早搏(PVC)风险及负荷水平之间的关系。方法 回顾性分析2020年10月至2021年12月间在郑州大学第一附属医院接受CT检查的频发PVC患者80例和非PVC患者160例临床资料。应用1∶1倾向性匹配得分(PSM)调整分析的评价标准。采用多因素Logistic回归方法分析频发PVC发生的危险因素。根据频发PVC患者的PVC负荷中位数分为高负荷组与低负荷组,分析EAT体积与频发PVC负荷水平之间的关系。结果 在未调整和PSM调整后的队列中,频发PVC患者的EAT体积明显大于对照组(P均<0.001)。多因素Logistic回归分析表明EAT体积是频发PVC的独立危险因素(P均<0.001)。在频发PVC患者中,高负荷组的EAT体积较大。结论 频发PVC患者较对照组而言,具有更大的EAT体积,并且EAT体积是频发PVC的一个重要的独立预测因素。EAT体积作为一种易测定的定量指标,为区分频发PVC患者提供了新思路。Objective The aim of this study was to investigate the relationship between epicardial adipose tissue volume(EAT) and the risk and load level of frequent premature ventricular complexes(PVC). Methods Retrospective analysis of 80 patients with frequent PVCs and 160 patients without PVCs who underwent computed tomography at the First Affiliated Hospital of Zhengzhou University between October 2020 and December 2021.The evaluation criteria of the 1∶1 propensity to match score(PSM) adjusted analysis were applied. Multifactorial logistic regression was used to analyze the risk factors for the occurrence of frequent PVCs. The relationship between EAT volume and the load level of frequent PVCs was analyzed according to the median number of patients with frequent PVCs divided into a high PVCs burden group and a low PVCs burden group. Results In both the unadjusted and PSM-adjusted cohorts, EAT volume was significantly greater in patients with frequent PVCs than in controls(both P<0.001).Multifactorial logistic regression analysis showed that EAT volume was an independent risk factor for frequent PVCs.(all P<0.001) In patients with frequent PVC,EAT volume was higher in the high PVCs burden group. Conclusion Patients with frequent PVCs have larger EAT volumes compared with controls, and EAT volume is an important independent predictor of freguent PVCs. EAT volume, as an easily measured quantitative index, provides a new insight to differentiate patients with frequent PVCs.

关 键 词：心外膜脂肪组织 频发室性早搏 计算机断层扫描 

分 类 号：R541.75[医药卫生—心血管疾病] R816.2[医药卫生—内科学]