羚角钩藤汤辅助西医治疗对中风后偏瘫患者中医症候、肢体功能的影响研究  

Effect of Lingjiao Gouteng Decoction on TCM Symptoms and Limb Function of Hemiplegic Patients After Stroke

作　　者：孙书芳 张少朋 Sun Shufang;Zhang Shaopeng(Traditional Chinese Medicine Department,Pingdingshan Second People’s Hospital,Pingdingshan,Henan,467000,China)

机构地区：[1]平顶山第二人民医院中医内科,河南平顶山467000

出　　处：《黑龙江医学》2024年第12期1450-1452,共3页Heilongjiang Medical Journal

基　　金：河南省医学科技攻关项目(LHGJ202102173)。

摘　　要：目的:观察羚角钩藤汤辅助西医治疗对改善中风后偏瘫患者中医症候、肢体功能的影响。方法:选取2020年7月—2022年2月平顶山市第二人民医院收治的129例中风后偏瘫患者作为研究对象,经随机数表法分为观察组(65例,予以中药羚角钩藤汤+西医治疗)和对照组(64例,仅予以西医治疗),比较两组患者治疗后的中医症候、肢体功能及脑组织血液流变学改善情况,对所有患者开展为期6个月的短期随访,观察患者脑神经功能恢复情况以及药物相关副反应发生情况。结果:治疗后,观察组的头痛眩晕、心烦易怒等主证以及面赤身热,气粗口臭等次证均低于对照组,差异有统计学意义(t=3.252、2.760、2.895、3.255,P<0.05);治疗后,观察者的Fugl-Meyer运动功能评分量表(FMA)高于对照组,差异有统计学意义(t=3.016、3.220,P<0.05);治疗后,观察组血浆黏度(PSV)、全血高切黏度(HSV)、全血低切黏度(LSV)均低于对照组,差异有统计学意义(t=3.021、3.000、3.498,P<0.05);随访期间,观察组的卒中量表(NIHSS)评分低于对照组,改良Barthel指数(MBI)评分高于对照组,差异有统计学意义(t=2.950、3.081,P<0.05);随访期间,观察组的不良反应发生率略高于对照组,差异无统计学意义(χ^(2)=0.160,P>0.05)。结论:在予以中风后偏瘫患者常规西医治疗的同时采用羚角钩藤汤配合治疗可促进患者症候恢复,还可以有效改善患者肢体功能、促进脑组织血液流变学及神经功能恢复,且此疗法安全性较高。Objective:To observe the effect of Lingjiao Gouteng decoction on improving the symptoms of traditional Chinese medicine and limb function of hemiplegic patients after stroke.Methods:129 cases of hemiplegia after stroke from July 2020 to February 2022 were selected.They were divided into the observation group(65 cases were treated with Lingjiao Gouteng Decoction+western medicine)and the control group(64 cases were treated with western medicine only).The improvement of symptoms,limb functions and cerebral blood rheology of the two groups after treatment were compared.All patients were followed up for a short period of 6 months.The recovery of brain nerve function and adverse reactions were observed.Results:After treatment,the main symptoms such as headache,dizziness,irritability,and secondary symptoms such as naked skin,coarse breath and bad breath in the observation group were lower than those in the control group,and the difference was statistically significant(t=3.252,2.760,2.895,3.255;P<0.05).After treatment,the Fugl-Meyer Motor Function Rating Scale(FMA)of the observation group was higher than that of the control group,and the difference was statistically significant(t=3.016,3.220;P<0.05).After treatment,PSV,HSV and LSV were lower than the control group,and the difference was statistically significant(t=3.021,3.000,3.498;P<0.05).During the follow-up period,NIHSS in the observation group was lower than that in the control group and MBI control group,and the difference was statistically significant(t=2.950,3.081;P<0.05).After treatment,the adverse reaction rate of observation group was higher than that of the control group,and the difference was statistically significant(χ^(2)=0.160,P>0.05).Conclusion:The combination of traditional western medicine and Lingjiao Gouteng decoction for post-stroke hemiplegia patients can promote the recovery of symptoms,improve the limb function of patients,and promote the recovery of cerebral blood rheology and nerve function.

关 键 词：中风后偏瘫 羚角钩藤汤 西医治疗 中医症候 肢体功能 脑血液流变学 神经功能 不良反应 

分 类 号：R25[医药卫生—中医内科学]