中药黄芪的药理作用分析及临床应用效果  

Pharmacological Analysis and Clinical Application Effects of Traditional Chinese Medicine Huangqi

作　　者：董立[1] 丛绍强[1] 程明丽 王丹 史家文[1] DONG Li;CONG Shaoqiang;CHENG Mingli;WANG Dan;SHI Jiawen(Office of Drug Clinical Trial Institutions,Tai′an City Central Hospital/Tai′an Central Hospital Affiliated to Qingdao University/Mount Taishan Medical Center,Tai′an Shandong 271000,China)

机构地区：[1]泰安市中心医院/青岛大学附属泰安市中心医院/泰山医养中心药物临床试验机构办公室,山东泰安271000

出　　处：《中国卫生标准管理》2024年第11期126-130,共5页China Health Standard Management

摘　　要：目的分析中药黄芪的药理作用及其临床应用效果。方法选取2022年10月—2023年10月青岛大学附属泰安市中心医院采用黄芪治疗的88例患者作为观察组,另选择同期应用西医治疗的88例作为对照组,观察运用中药黄芪后患者的临床疗效。结果观察组(95.45%)急性心肌梗死合并心力衰竭总有效率高于对照组(72.73%)(P<0.05)。观察组(90.91%)扩张型心肌病伴心力衰竭总有效率高于对照组(68.18%)(P<0.05)。观察组糖尿病周围神经病变总有效率(100%)高于对照组(77.27%)(P<0.05)。观察组脑血栓总有效率(95.45%)高于对照组(68.18%)(P<0.05)。结论中药黄芪在治疗糖尿病周围神经病变、急性心肌梗死伴心衰、脑血栓后遗症以及扩张型心肌病合并心力衰竭患者中疗效较理想,为临床治疗提供有力依据,同时也为中药在心血管和神经系统疾病治疗中的应用提供新思路。但仍需要进一步的研究来验证其机制和安全性。Objective To analyze the pharmacological effects and clinical application effects of important Astragalus membranaceus.Methods From October 2022 to October 2023,a total of 88 patients who received treatment with Astragalus membranaceus from Tai′an Central Hospital Affiliated to Qingdao University were selected as observation group.88 cases treated with Western medicine in the same period were selected as control group.The clinical efficacy of using traditional Chinese medicine Astragalus membranaceus were observed.Results The total effective rate of acute myocardial infarction combined with heart failure in the observation group(95.45%)was higher than that in the control group(72.73%)(P<0.05).The total effective rate of dilated cardiomyopathy with heart failure in the observation group(90.91%)was higher than that in the control group(68.18%)(P<0.05).The total effective rate of diabetes peripheral neuropathy in the observation group(100%)was higher than that in the control group(77.27%)(P<0.05).The total effective rate of cerebral thrombosis in the observation group(95.45%)was higher than that in the control group(68.18%)(P<0.05).Conclusion Astragalus membranaceus,a traditional Chinese medicine,has an ideal effect in the treatment of diabetic peripheral neuropathy,acute myocardial infarction with heart failure,sequelae of cerebral thrombosis and Dilated cardiomyopathy with heart failure,it is applicable in various clinical diseases and has good drug value,providing strong basis for clinical treatment.At the same time,it also provides new ideas for the application of traditional Chinese medicine in the treatment of cardiovascular and neurological diseases,however,further research is needed to verify its mechanism and security.

关 键 词：中药黄芪 药理作用 糖尿病周围神经病变 急性心肌梗死 心力衰竭 脑血栓 扩张型心肌病 

分 类 号：R285[医药卫生—中药学]