低剂量CT仿真结肠镜在结直肠肿瘤中的应用  

The application of low-dose CT virtual colonoscopy in colorectal tumor

作　　者：杜志琴[1] 朱彩艳 陶建祥 王丽娟[1] 周忠春 王若天[2] DU Zhiqin;ZHU Caiyan;TAO Jianxiang;WANG Lijuan;ZHOU Zhongchun;WANG Ruotian(Department of Radiology,Yanan Hospital Affiliated to Kunming Medical University,Key Laboratory of Tumor Immunological Prevention and Treat ment of Yunnan Province,Kunming 650051,China;Department of General Surgery,Yanan Hospital Affiliated to Kunming Medical University,Key Laboratory of Tumor Immunological Prevention and Treat ment of Yunnan Province,Kunming 650051,China)

机构地区：[1]昆明医科大学附属延安医院、云南省肿瘤免疫防治研究重点实验室放射科,云南昆明650051 [2]昆明医科大学附属延安医院、云南省肿瘤免疫防治研究重点实验室普外一科,云南昆明650051

出　　处：《实用放射学杂志》2024年第5期737-740,共4页Journal of Practical Radiology

基　　金：云南省肿瘤免疫防治研究重点实验室开放课题(2017DG004-03)。

摘　　要：目的探讨低剂量CT仿真结肠镜(LDCTVC)在结直肠肿瘤中的应用。方法47例结直肠病变患者行低剂量CT腹部扫描(低剂量组),同期正常体质量指数(BMI)患者15例行常规剂量CT腹部扫描(常规剂量组),记录容积CT剂量指数(CTDI_(vol))、剂量长度乘积(DLP)、仿真结肠镜和光学肠镜结果。结果正常BMI低剂量组和常规剂量组的有效剂量分别为(2.86±0.47)mSv、(4.87±1.15)mSv,2组CTDI_(vol)、DLP差异有统计学意义(P<0.05)。低剂量组真阳性14例,假阳性4例,假阴性5例,真阴性24例,LDCTVC诊断结直肠黏膜病变的敏感度73.7%,特异度85.7%,Kappa值0.6。结论LDCTVC能降低50%有效剂量并对结直肠黏膜病变有很好诊断价值,更能弥补肠镜检查的不足,对肠壁黏膜外病变做出准确判断。Objective To investigate the application of low-dose computed tomography virtual colonoscopy(LDCTVC)in colorectal tumor.Methods Forty-seven colorectal tumor were given low-dose CT abdominal scan(low-dose group),15 patients with normal body mass index(BMI)who received routine-dose CT abdominal scan at the same period(routine-dose group).Volume CT dose index(CTDI_(vol)),dose length product(DLP),virtual colonoscopy and optical colonoscopy results were recorded.Results Theeffective dose with normal BMI was(2.86±0.47)mSv and(4.87±1.15)mSv in the low-dose and routine-dose groups,respectively.The CTDI_(vol)and DLP between the two groups were statistically significant(P<0.05).There were 14 cases of true positive,4 cases of false positive,5 cases of false negative and 24 cases of true negative in the low-dose group.The sensitivity,specificity and Kappa value of LDCTVC in the diagnosis of colorectal mucosal lesions were 73.7%,85.7%,and 0.6.Conclusion LDCTVC can reduce the effective dose by 5o%and has a good diagnostic value for colorectal mucosal lesions,which can make up for the deficiency of colonoscopy and make accurate judgment of extra-mucosal lesions of the bowel wall.

关 键 词：低剂量 计算机体层成像 仿真结肠镜 结直肠肿瘤 

分 类 号：R814.42[医药卫生—影像医学与核医学] R735.3[医药卫生—放射医学]