聚多卡醇泡沫联合无水乙醇硬化治疗儿童下肢静脉畸形  

The sclerotherapy of polidocanol foam combined with absolute ethanol in the treatment of lower extremity venous malformation in children

作　　者：潘登 尹传高 汪松 齐炜炜 PAN Deng;YIN Chuangao;WANG Song;QI Weiwei(Imaging Center,Anhui Province Children's Hospital,Hefei 230051,China)

机构地区：[1]安徽省儿童医院影像中心,安徽合肥230051

出　　处：《实用放射学杂志》2024年第5期793-795,共3页Journal of Practical Radiology

摘　　要：目的探讨聚多卡醇泡沫联合无水乙醇在儿童下肢静脉畸形(VM)治疗中的应用价值。方法回顾性分析20例下肢VM患儿的临床资料,均行MRI检查确诊下肢VM,所有患儿在数字减影血管造影(DSA)引导下经皮穿刺造影后行硬化剂注射治疗,术中根据造影分型、病灶范围的大小、流速选择不同的硬化剂进行治疗。病灶范围较小、位置表浅且流速较慢的VM仅用聚多卡醇泡沫治疗,而病灶范围较大、流速较快的VM联合应用无水乙醇治疗。术后1个月根据临床症状及MRI检查评判疗效。结果20例患儿经过硬化治疗,15例治愈,3例显效,2例有效。部分患儿术后48h内出现不同程度疼痛及肿胀,予以对症处理,短期内症状消失,1例病灶表面皮肤破溃,经治疗后愈合。结论聚多卡醇泡沫联合无水乙醇治疗儿童下肢VM安全、有效,二者联合使用可提高疗效,减少术后并发症的发生。Objective To explore the application value of polidocanol foam combined with absolute ethanol in the treatment of lower extremity venous malformation(VM)in children.Methods The clinical data of 20 children with lower extremity VM were analyzed retrospectively.All of these children were diagnosed with VM of lower extremity by MRI and were treated with digital subtraction angiography(DSA)guided percutaneous sclerotherapy.Different hardening agents were selected according to the classification,the size of the lesion range and the flow rate during the operation.The VM with small lesions range,shallow location and slower velocity were treated with polidocanol foam only,while the VM with larger lesion range and faster velocity were combined treated with absolute ethanol.Clinical symptoms and MRI were used to evaluate the curative effect one month after operation,Results Twenty children received sclerotherapy.After the treatment,15 cases were cured,3 cases showed significantly effective,and 2 cases were effective.Some of the children had pain and swelling of different degrees within 48 hours after operation,who were given symptomatic treatment,and the symptoms disappeared in the short time.The skin of the lesion ulcerated in one case and the ulceration healed after treatment.Conclusion Polidocanol foam combined with absolute ethanol is safe and effective in the treatment of lower extremity VM in children,and the combination can improve the curative effect and reduce the occurrence of postoperative complications.

关 键 词：静脉畸形 硬化治疗 聚多卡醇 无水乙醇 

分 类 号：R543.6[医药卫生—心血管疾病] R815[医药卫生—内科学]