冠心病患者彩超下颈动脉弹性指标及心外膜脂肪层厚度与病情严重程度的关系分析  

Analyze the correlation of carotid artery elasticity indicators and epicardial fat thickness under color Doppler ultrasound with the severity of coronary heart disease

作　　者：肖娟 袁新春[2] 胡佳[2] XIAO Juan;YUAN Xinchun;HU Jia(Department of Functions,Ganzhou Hospital of Traditional Chinese Medicine,Ganzhou,Jiangxi,341000,China;Department of Ultrasound Medicine,the First Affiliated Hospital of Nanchang University,Ganzhou,Jiangxi,330006,China)

机构地区：[1]赣州市中医院功能科,江西赣州341000 [2]南昌大学第一附属医院超声医学科,江西赣州330006

出　　处：《当代医学》2024年第7期54-57,共4页Contemporary Medicine

摘　　要：目的分析冠心病(CHD)患者彩超下颈动脉弹性指标、心外膜脂肪层厚度(EFT)与病情严重程度的关系。方法选取2019年1月至2022年2月赣州市中医院收治的120例CHD患者作为实验组,根据患者病情严重程度分为A组(轻度,n=30)、B组(中度,n=48)、C组(重度,n=42),另选取同期接受健康检查的50名健康者作为对照组。采用彩超检查患者颈动脉弹性指标、EFT并探讨两者与病情严重程度的关系。结果实验组内中膜厚度(IMT)、血管僵硬度(β)、弹性模量(Ep)均高于对照组,脉搏波传导速度(PWV-β)快于对照组,顺应性(AC)低于对照组,差异有统计学意义(P<0.05)。C组IMT、β、Ep均高于A组和B组,PWV-β快于A组和B组,AC低于A组和B组,且B组Ep高于A组,PWV-β快于A组,AC低于A组,差异有统计学意义(P<0.05),其余组间两两比较差异无统计学意义。实验组EFT厚于对照组,差异有统计学意义(P<0.05);C组EFT厚于B组、A组,B组厚于A组,差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,IMT、β、Ep、AC、EFT升高,PWV-β加快,AC降低是影响CHD患者病情严重程度的独立危险因素(OR>1,P<0.05)。结论IMT、β、Ep、AC、EFT升高,PWV-β加快,AC降低是影响CHD患者病情严重程度的独立危险因素,颈动脉弹性指标、EFT可作为评估CHD患者疾病严重程度的重要指标,值得临床推广应用。Objective To analyze the correlation of carotid artery elasticity indicators and epicardial fat thickness(EFT)under color Doppler ul-trasound with the severity of coronary heart disease(CHD).Methods 120 patients with CHD treated in Ganzhou Traditional Chinese Medicine Hos-pital from January 2019 to February 2022 were selected as the experimental group,and they were divided into the group A(mild,n=30),the group B(moderate,n=48)and the group C(severe,n=42)according to the severity of disease,50 healthy individuals who received health examination during the same period were selected as the control group.The carotid artery elasticity indicators and EFT were measured with color Doppler ultrasound,and their correlation with the severity of the disease was explored.Results The intima-media thickness(IMT),vascular stiffness(β)and elasticmod-ulus(Ep)in the experimental group were higher than those in the control group,the pulse wave velocity-β(PWV-β)was faster than that in the control group,and the compliance(AC)was lower than that in the control group,the differences were statistically significant(P<0.05).IMT,βand Ep in the group C were higher than those in the group A and the group B,PWV-βwas faster than that in the group A and the group B,AC was lower than that in the group A and the group B,Ep in the group B was higher than that in the group A,PWV-βwas faster than that in the group A,AC was lower than that in the group A,the differences were statistically significant(P<0.05),there were no significant differences between the other groups.The EFT of the experimental group was thicker than that in the control group,and the difference was statistically significant(P<0.05);the EFT in the group C was thicker than that in the group B and the group A,and the EFT in the group B was thicker than that in the group A,the differences were statistically significant(P<0.05).Multivariate Logistic regression analysis showed that IMT,β,Ep,AC,EFT increased,PWV-βaccelerated,and AC decreased were independent risk factors affecting

关 键 词：冠心病 颈动脉 弹性 心外膜脂肪层厚度 

分 类 号：R541.4[医药卫生—心血管疾病]