外周血循环浆细胞流式细胞术检测在浆细胞病中的应用中国专家共识(2024年版)  

Chinese expert consensus on the application of flow cytometry for the detectin of circulating plasma cells in plasma cell disorders (2024)

作　　者：中华医学会血液学分会浆细胞疾病学组 中华医学会血液学分会实验诊断学组 胡豫[2] 吴德沛[3] 黄晓军[4] 孙春艳[2] 蔡丽 Plasma Cell Disease Group,Chinese Society of Hematology,Chinese Medical Association;Laboratory Diagnosis Group,Chinese Society of Hematology,Chinese Medical Association;Hu Yu;Wu Depei;Huang Xiaojun(不详;Institute of Hematology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China;the First Affiliated Hospital of Soochow University,Suzhou 215006,China;Peking University People's Hospital,Beijing 100044,China)

机构地区：[1]不详 [2]华中科技大学同济医学院附属协和医院,武汉430022 [3]苏州大学附属第一医院,苏州215006 [4]北京大学人民医院,北京100044

出　　处：《中华血液学杂志》2024年第4期313-321,共9页Chinese Journal of Hematology

摘　　要：流式细胞术检测外周血循环浆细胞(circulating plasma cells,CPCs)在浆细胞病的诊疗中已经展示出了重要价值。为促进流式细胞术检测CPCs在临床中的规范使用,特制定本共识。本共识依据循证原则,明确了意义未明的单克隆免疫球蛋白血症、冒烟型骨髓瘤、多发性骨髓瘤和浆细胞白血病进行CPCs检测的时机与价值,并对CPCs的流式细胞术检测方法进行规范。Flow cytometry plays an important role in the diagnosis and treatment of plasma cell diseases,particularly in the detection of circulating plasma cells(CPCs)in the peripheral blood.A consensus about the normalized use of flow cytometry in detection of CPCs in peripheral blood in clinical practice has been achieved.This consensus is founded on evidence-based principles,which elucidates the timing and value of flow cytometry for the detection of CPCs in the monoclonal gammopathy of undetermined significance,smoldering myeloma,multiple myeloma,and plasma cell leukemia and standardizes flow cytometry in the detection of CPCs in plasma cell diseases.

关 键 词：浆细胞病 流式细胞术 循环浆细胞 

分 类 号：R551.2[医药卫生—血液循环系统疾病]