孕早期妇女甲状腺功能筛查结果观察分析  

Observation and Analysis of Thyroid Function Screening Results in Early Pregnant Women

作　　者：靳文秀 苏艺 彭习芬 班钟月 Jin Wenxiu;Su Yi;Peng Xifen;Ban Zhongyue(Qingzhen First People's Hospital,Guiyang 551400,Guizhou Province,China)

机构地区：[1]清镇市第一人民医院,贵州贵阳551400

出　　处：《中外医药研究》2024年第12期139-141,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

基　　金：清镇市软科学研究项目(编号:[2021]清科合同字第27号)。

摘　　要：目的:分析孕早期妇女甲状腺功能筛查结果。方法:选取2018年1月—2021年1月于清镇市第一人民医院接受甲状腺功能筛查的孕早期妇女800例作为研究对象,均接受甲状腺功能筛查,分析其检查结果,并针对甲状腺功能减退孕妇进行随访干预,每年选入50例甲状腺功能筛查结果为正常的孕早期妇女作为对照组,共计200例。比较甲状腺功能减退孕妇和正常孕妇的甲状腺功能筛查结果,并观察其妊娠结局。结果:在800例孕早期妇女中,150例存在甲状腺功能减退,占比为18.75%(150/800)。甲状腺功能减退组孕妇促甲状腺激素高于对照组,三碘甲状腺原氨酸、甲状腺激素、游离三碘甲状腺原氨酸、游离甲状腺激素低于对照组,差异有统计学意义(P<0.05)。接受治疗组甲状腺功能减退孕妇不良妊娠结局发生率低于未接受治疗组,差异有统计学意义(P<0.05)。结论:对孕早期妇女实施甲状腺功能筛查的临床价值突出,能够及时发现甲状腺功能异常情况并进行治疗,有助于降低不良妊娠结局发生率。Objective:To analyze the results of thyroid function screening in women in early pregnancy.Methods:Eight hundred cases of women in early pregnancy who received thyroid function screening in Qingzhen First People's Hospital from January 2018 to January 2021 were selected as study subjects,and all of them received thyroid function screening.The results of the screening were analyzed,and follow-up interventions were carried out for hypothyroid pregnant women,and fifty cases of women with normal thyroid function screening results in early pregnancy were selected as the control group every year,totaling two hundred cases.The results of thyroid function screening were compared between hypothyroid pregnant women and normal pregnant women,and their pregnancy outcomes were observed.Results:Among the eight hundred women in early pregnancy,one hundred and fifty cases had hypothyroidism,accounting for 18.75%(150/800);thyroid stimulating hormone in pregnant women in the hypothyroidism group was higher than that in the control group,and triiodothyronine,thyroid hormones,free triiodothyronine,and free thyroid hormones were lower than those in the control group,and the difference was statistically significant(P<0.05);the incidence of adverse pregnancy outcomes in hypothyroid pregnant women in the treated group was lower than that in the untreated group,and the difference was statistically significant(P<0.05).Conclusion:The clinical value of thyroid function screening for women in early pregnancy is outstanding,which can timely detect and treat thyroid function abnormalities and help reduce the incidence of adverse pregnancy outcomes.

关 键 词：甲状腺功能筛查 孕早期 甲状腺功能减退 妊娠结局 

分 类 号：R714.256[医药卫生—妇产科学]