离子色谱法测定桂林西瓜霜含片中硫酸钠的含量  

Determination of Sodium Sulfate Content in Guilin Watermelon Frost Buccal Tablets by Ion Chromatography

作　　者：黄瑞明 周丽霞 雷肖琳[1] 秦霜 周晓妮 邹洵 Huang Ruiming;Zhou Lixia;Lei Xiaolin;Qin Shuang;Zhou Xiaoni;Zou Xun(Guilin Sanjin Pharmaceutical Co.,Ltd.,Guilin 541000,China)

机构地区：[1]桂林三金药业股份有限公司,广西桂林541000

出　　处：《山东化工》2024年第10期149-150,153,共3页Shandong Chemical Industry

摘　　要：目的:使用离子色谱法测定桂林西瓜霜含片中硫酸钠的含量。方法:采用以烷醇季铵为功能基的乙基乙烯基苯-二乙烯基苯聚合物树脂作为填料的阴离子交换柱,以25 mmol/L氢氧化钾溶液为淋洗液;理论板数按硫酸根离子峰计算应不低于2 000。结果:硫酸钠进样量在0.924 5~7.396μg的范围内,硫酸钠进样量与硫酸钠峰面积呈良好的线性关系,r=1.000 0。结论:本方法操作简单、方法可靠、结果准确、灵敏度高、重现性好,可作为桂林西瓜霜含片中硫酸钠的含量控制的方法。Objective:To determine the content of sodium sulfate in Guilin Watermelon Frost Buccal Tablets using ion chromatography.Method:An anion exchange column was used using ethyl vinyl benzene divinylbenzene polymer resin with quaternary ammonium alkoxide as the functional group as the filler,and a 25 mmol/L potassium hydroxide solution was used as the eluent;The theoretical number of plates should not be less than 2000 when calculated based on the sulfate ion peak.Result:The injection amount of sodium sulfate ranged from 0.9245 to 7.396μg.Within this range,there is a good linear relationship between the injection amount of sodium sulfate and the peak area of sodium sulfate,with r=1.0000.Conclusion:This method is simple to operate,reliable,accurate,highly sensitive,and has good reproducibility.It can be used as a method for controlling the content of sodium sulfate in Guilin Watermelon Frost Buccal Tablets.

关 键 词：离子色谱法 硫酸根离子 桂林西瓜霜含片 

分 类 号：TQ461[化学工程—制药化工]