血清镁在急性肾损伤诊疗中的研究进展  

Research progress of serum magnesium in the diagnosis and treatment of acute kidney injury

作　　者：潘炽星 李紫韵 陈纯波 PAN Chixing;LI Ziyun;CHEN Chunbo(First School of Clinical Medicine,Guangdong Medical University,Zhanjiang 524023,Guangdong Province,China;Department of Intensive Care Medicine,Shenzhen People's Hospital,Shenzhen 518020,Guangdong Province,China;Department of Intensive Care Medicine,Guangdong Provincial People's Hospital,Guangzhou 510080,China)

机构地区：[1]广东医科大学第一临床医学院,广东湛江524023 [2]深圳市人民医院重症医学科,广东深圳518020 [3]广东省人民医院重症医学科,广州510080

出　　处：《医学新知》2024年第6期707-716,共10页New Medicine

基　　金：国家自然科学基金面上项目(82172162)。

摘　　要：急性肾损伤(acute kidney injury,AKI)是威胁健康的急重症,在临床工作中常见。AKI的发生往往延长患者康复时间并降低其长期生活质量。由于缺乏特定的治疗手段,早诊断并对症治疗是提高AKI患者预后的关键。血清镁浓度的变化与AKI的发生及预后存在一定关联,并在AKI的诊断及治疗中发挥重要作用。本文就镁的分布与稳态调节、血清镁与AKI的相关性及镁离子紊乱诱发AKI的可能机制进行介绍,并列举了镁补充剂在AKI防治中的应用实例,旨在加强临床医师对人体镁稳态的认识,及时纠正镁失衡以改善AKI患者的预后。Acute kidney injury(AKI)is an acute and severe disease that threat to human health significantly.The occurrence of AKI tends to delay patients’recovery and reduces their long-term quality of life.In the absence of specific treatments,early diagnosis and intervention are crucial for improving the prognosis of AKI patients.The alteration in serum magnesium concentration is associated with the occurrence and prognosis of AKI,and play an important role in its diagnosis and treatment.This review presents a summary of the distribution and homeostatic regulation of magnesium,as well as the correlation between serum magnesium imbalance and AKI,the potential mechanism of AKI induced by magnesium ion disorders,and cites the application of magnesium supplementation in the prevention and treatment of AKI.By enhancing public understanding of human magnesium homeostasis through this article,this article aims to raise awareness among clinicians regarding the relationship between serum magnesium imbalance and AKI,and to correct dysmagnesemia in a timely manner,to improved prognosis for AKI patients ultimately.

关 键 词：急性肾损伤 血清镁 相关性 诊断 预后 

分 类 号：R69[医药卫生—泌尿科学]