米索前列醇和卡前列甲酯栓促进剖宫产术后胃肠功能恢复的效果分析  

Analysis of Effect of Misoprostol and Carboprost Methylate Suppositories on Promoting Recovery of Gastrointestinal Function after Cesarean Section

作　　者：任熙[1] 晁佳 田秀娟[1] 闫利荣[1] REN Xi;CHAO Jia;TIAN Xiu-juan;YAN Li-rong(Department of Obstetrics and Gynecology,The Second Affiliated Hospital of Hebei North University,Zhangjiakou,Hebei 075100,China)

机构地区：[1]河北北方学院附属第二医院妇产科,河北张家口075100

出　　处：《河北北方学院学报（自然科学版）》2024年第8期8-11,共4页Journal of Hebei North University:Natural Science Edition

基　　金：张家口市重点研发计划项目(No.2221051D)。

摘　　要：目的 探讨米索前列醇和卡前列甲酯栓促进剖宫产术后胃肠功能恢复的效果。方法 200例剖宫产分娩的产妇按干预方式分为米索前列醇舌下组68例、卡前列甲酯栓直肠组58例及缩宫素组74例。米索前列醇舌下组术毕即给予舌下含服米索前列醇400μg,卡前列甲酯栓直肠组术毕即给予1 mg卡前列甲酯栓肛塞,缩宫素组仅静脉滴注缩宫素。观察各组肠鸣音出现时间、术后首次排气、排便时间及腹胀、腹痛发生情况。结果 与缩宫素组相比,米索前列醇舌下组、卡前列甲酯栓直肠组产妇肠鸣音出现时间及术后首次排气、排便时间明显缩短,差异有统计学意义(P<0.01),且米索前列醇舌下组短于卡前列甲酯栓直肠组(P<0.01);腹痛、腹胀、胃肠功能紊乱发生率低于缩宫素组(P<0.01)。结论 米索前列醇和卡前列甲酯栓能有效促进剖宫产术后胃肠道功能恢复,降低剖宫产术后胃肠功能不良后果发生率,且米索前列醇改善胃肠功能效果更优,更适用于基层医院,值得临床参考应用.Objective To investigate the effect of misoprostol and carboprost methylate suppositories on the recovery of gastrointestinal function after cesarean section.Methods A total of 200 cases of cesarean section were divided into 68 cases of misoprostol sublingual group,58 cases of carboprost methylate suppository rectal group and 74 cases of oxytocin group according to the intervention method.The sublingual misoprostol group was given sublingual misoprostol 400μg at the end of the operation.The rectal group was given 1 mg carboprost methylate suppository anal plug at the end of the operation.The oxytocin group was only given intravenous infusion of oxytocin.The occurrence time of bowel sounds,the time of first exhaust and defecation after operation,and the occurrence of abdominal distension and abdominal pain were observed.Results Compared with the oxytocin group,the occurrence time of bowel sounds and the time of first exhaust and defecation after operation were significantly shortened in the misoprostol sublingual group and the carboprost methylate suppository rectal group(P<0.01),and the misoprostol sublingual group had shorter time than that of the carboprost methylate suppository rectal group(P<0.01).The incidence of abdominal pain,abdominal distension and gastrointestinal dysfunction was lower than that of the oxytocin group(P<0.01).Conclusion Misoprostol and carboprost methylate suppositories can effectively promote the recovery of gastrointestinal function after cesarean section and reduce the incidence of gastrointestinal dysfunction after cesarean section.Misoprostol is more effective in improving gastrointestinal function and is more suitable for primary hospitals,which is worthy of clinical reference.

关 键 词：剖宫产术 胃肠功能 缩宫素 米索前列醇 卡前列甲酯栓 

分 类 号：R614[医药卫生—麻醉学] R719.8[医药卫生—外科学]