基于HR-MR-VWI探讨ICAS斑块特征、血管壁参数与缺血性脑卒中发病的关系  

Exploring the Relationship between ICAS Plaque Characteristics,Vascular Wall Parameters,and Ischemic Stroke Incidence Based on HR-MR-VWI

作　　者：张杨 赵启利[2] 张曦 许涛[2] 张雅娟 ZHANG Yang;ZHAO Qi-li;ZHANG Xi;XU Tao;ZHANG Ya-juan(Department of Radiology,Langfang People's Hospital,Langfang 065000,Hebei Province,China;Department of Magnetic Resonance and CT,Langfang 065000,Hebei Province,China)

机构地区：[1]廊坊市人民医院放射诊断科,河北廊坊065000 [2]廊坊市人民医院磁共振CT科,河北廊坊065000

出　　处：《中国CT和MRI杂志》2024年第6期47-49,共3页Chinese Journal of CT and MRI

基　　金：河北省科学技术厅项目(182777176)。

摘　　要：目的 分析基于HR-MR-VWI探讨ICAS斑块特征、血管壁参数与缺血性脑卒中发病的关系。方法 选择我院2018年12月至2020年12月间收治的100例疑似缺血性脑卒中患者作为观察组及50例健康体检者作为对照组;所有受试者行HR-MR-VWI扫描检查;对观察组患者进行为期2年的随访观察,记录其发生脑卒中事件的情况,并依照患者是否出现脑卒中分为脑卒中亚组和无症状亚组;采用Spearman相关性检验及logistics回归模型分析缺血性脑卒中发病的相关影响及危险因素。结果 观察组患者血管壁LARL、OWAMLN、WAMLN水平明显高于对照组,LAMLN水平较对照组低,且差异明显(P<0.05);脑卒中组患者血管壁LARL、OWAMLN、WAMLN、狭窄率、斑块负荷、重构指数水平明显高于无症状组,LAMLN水平明显低于无症状组,且差异存在统计学意义(P<0.05);LARL、OWAMLN、WAMLN、狭窄率、斑块负荷及重构指数与缺血性脑卒中发病呈显著正相关关系,LAMLN与缺血脑卒中发病呈显著负相关关系,且存在统计学意义(P<0.05);高LARL、低LAMLN、高OWAMLN、高WAMLN、高狭窄率、高斑块负荷及高重构指数影响缺血性脑卒中发病的独立性危险因素,且存在统计学意义(P<0.05)。结论 基于HR-MR-VWI检测ICAS患者中斑块特征、血管壁参数是影响缺血性脑卒中发病的独立性威胁因素。Objective To analyze the relationship between ICAS plaque characteristics,vessel wall parameters and ischemic stroke based on HR-MR-VWI.Methods 100 patients with suspected ischemic stroke admitted to our hospital from December 2018 to December 2020 were selected as the observation group and50 healthy subjects were selected as the control group;all subjects underwent HR-MR-VWI scanning;The patients were followed up for 2 years,and their stroke events were recorded,and they were divided into a stroke subgroup and an asymptomatic subgroup according to whether they had a stroke;Spearman's correlation test and logistics regression model were used to analyze the impact and risk factors of ischemic stroke.Results The LARL,OWAMLN,and WAMLN in the observation group were higher than control group statistically,LAMLN were obvious lower than the control group statistically(P<0.05).The stenosis rate,plaque burden,and remodeling index levels were obvious higher than asymptomatic group,and the LAMLN level was obvious lower than that of the asymptomatic group,and the difference was statistically obvious(P<0.05);LARL,OWAMLN,WAMLN,stenosis rate,plaque The load and remodeling index were obvious positively correlated with the incidence of ischemic stroke,and LAMLN was obvious negatively correlated with the incidence of ischemic stro ke,and there was statistical obvious(P<0.05);high LARL,low LAMLN,high OWAMLN,high WAMLN,high stenosis rate,high plaque burden and high remodeling index were independent risk factors for ischemic stroke,and there was statistical obvious(P<0.05).Conclusion Based on HR-M R-VWI detection of plaque characteristics and vessel wall parameters in patients with ICAS,they are independent risk factors affecting the incidence of ischemic st roke.

关 键 词：高分辨磁共振血管壁成像 颅内动脉粥样硬化 斑块特征 血管壁参数 缺血性脑卒中 

分 类 号：R543.12[医药卫生—心血管疾病]