Xpert、TB-IGRA及CT诊断脊柱结核的价值  

The value of Xpert,TB-IGRA,and CT for the diagnosis of spinal tuberculosis

作　　者：张佳伟 董聪慧 杨文帅 高亚丽 郭彦娇 武永萍 Zhang Jiawei;Dong Conghui;Yang Wenshuai;Gao Yali;Guo Yanjiao;Wu Yongping(Zhangjiakou Infectious Disease Hospital,Zhangjiakou 075000,China)

机构地区：[1]张家口市传染病医院,河北张家口075000

出　　处：《现代科学仪器》2024年第3期156-160,共5页Modern Scientific Instruments

基　　金：张家口市2023年科技计划项目2322030D。

摘　　要：目的:探讨Xpert、TB-IGRA及CT对脊柱结核的诊断价值及CT检查病变情况。方法:选取89例疑似脊柱结核患者,均行病理、Xpert、TB-IGRA及CT检查,统计病理结果,比较Xpert、TB-IGRA、CT与病理结果,分析Xpert、TB-IGRA、CT对脊柱结核的诊断价值,并对比CT与病理检查脊柱结核病变情况。结果:89例疑似脊柱结核患者病理结果显示,阳性60例,阴性29例。CT诊断脊柱结核的阴性预测值、准确度高于Xpert;CT诊断脊柱结核的AUC值高于Xpert、TB-IGRA,且TB-IGRA高于Xpert(P<0.05)。CT检查脊柱结核病变为骨质破坏、韧带下播散占比与病理结果比较有差异(P<0.05)。结论:CT诊断脊柱结核的价值较高,对骨质破坏、韧带下播散的检出情况较好。Objective:To investigate the diagnostic value of Xpert,TB-IGRA and CT in the diagnosis of spinal tuberculosis and CT examination of the lesions.Methods:89 patients with suspected spinal tuberculosis were selected,all underwent pathological,Xpert,TB-IGRA,and CT.The pathological results were counted,diagnostic value of Xpert,TB-IGRA,CT and pathological were compared,the diagnostic value of Xpert,TB-IGRA,and CT for spinal tuberculosis were analyzed and the CT and pathologic examination of spinal tuberculosis lesions were compared.Results:The pathological results of 89 patients with suspected spinal tuberculosis showed 60 positive cases and 29 negative cases.The negative predictive value and accuracy of CT diagnosis of spinal tuberculosis were higher than that of Xpert;the AUC value of CT diagnosis of spinal tuberculosis was higher than that of Xpert,TB-IGRA,and TB-IGRA was higher than that of Xpert(P<0.05).The CT examination of the spinal tuberculosis lesion condition as bone destruction and subligamentous dissemination accounted for a significant difference compared with pathological(P<0.05).Conclusion:CT examination had a relatively high diagnostic value for spinal tuberculosis and its detection of bone destruction and subligamentous dissemination is better.

关 键 词：脊柱结核 Xpert Γ干扰素释放试验 电子计算机断层扫描 诊断价值 

分 类 号：R52[医药卫生—内科学]