共轭聚合物“电子舌”检测四环素类抗生素  

An"Electronic Tongue"Based on Conjugated Polymers for Tetracyclines Discrimination

作　　者：陈世勇 王杰 朱琰超 张丽娟 王贵友[1] 胡爱国[1] CHEN Shiyong;WANG Jie;ZHU Yanchao;ZHANG Lijuan;WANG Guiyou;HU Aiguo(Shanghai Key Laboratory of Advanced Polymeric Materials,School of Materials Science and Engineering,East China University of Science and Technology,Shanghai 200237,China)

机构地区：[1]华东理工大学材料科学与工程学院,上海市先进聚合物材料重点实验室,上海200237

出　　处：《华东理工大学学报（自然科学版）》2024年第3期354-359,共6页Journal of East China University of Science and Technology

基　　金：国家自然科学基金(22171083)。

摘　　要：通过将6种共轭聚合物(CPs)与水性聚氨酯(WPU)物理共混,制备了WPU包覆的荧光传感阵列,用以检测水中的四环素类抗生素(TCs)。WPU与CPs共混后制备的薄膜阵列形状规则,荧光亮度高且稳定。WPU基体在溶胀后,存在泡孔状的孔道结构,增大了附着于其中的CPs与水中待测物TCs的接触概率,增强了阵列的荧光响应。通过相机捕捉检测前后的荧光照片,并提取照片的红绿蓝(RGB)值,获得了18维向量数据库。通过主成分分析(PCA)和线性判别分析(LDA)等方法对数据进行降维处理。结果发现该荧光传感阵列具有良好的区分不同结构TCs的能力,LDA模型的分析预测准确度可达100%。这种WPU包覆CPs的荧光检测阵列具有制备便捷、成本低和稳定性好等优点,可望作为环境检测中的“电子舌”,检测并甄别水体中的污染物如四环素类抗生素。Six conjugated polymers(CPs)were physically blended with waterborne polyurethane(WPU)to prepare a WPU-wrapped fluorescence sensor array for the detection of tetracyclines(TCs)in water.The shape of the film array prepared by blending WPU with CPs is regular,and the fluorescence emission of the system is strong and stable.After swelling,an interconnected porous structure was formed in the WPU matrix,which increased the contact probability between the attached CPs and TCs in water,thus enhancing the fluorescence response of the array.The fluorescence images before and after TCs detection were captured by a camera,and the RGB(Red-Green-Blue)values of the photos were extracted to afford an 18-dimensional vector database.The dimensionality of the data was reduced by principal component analysis(PCA)and linear discriminant analysis(LDA).The results showed that the fluorescence sensor array had a good ability to discriminate structurally different TCs,and the prediction accuracy of the LDA model reached 100%.Our WPU-wrapped fluorescence detection array is advantageous in terms of simplicity in preparation,cost and stability,and is expected to be used as an"electronic tongue"in environmental surveillance to detect and identify pollutants such as TCs in water.

关 键 词：共轭聚合物 水性聚氨酯 荧光传感阵列 四环素类抗生素 环境监测 

分 类 号：O621.2[理学—有机化学]