多烯磷脂酰胆碱注射液致过敏性休克一例分析  

A case report of anaphylactic shock caused by Polyene phosphatidyl choline

作　　者：邬秀娟 邹艳 平耀东[1] WU Xiu-Juan;ZOU Yan;PING Yao-Dong(Department of Pharmacy,Inner Mongolia Hospital,Peking University Cancer Hospital(Affiliated Cancer Hospital of Inner Mongolia Medical University,Inner Mongolia Autonomous Region Cancer Hospital),Hohhot 010020,China)

机构地区：[1]北京大学肿瘤医院内蒙古医院(内蒙古医科大学附属肿瘤医院、内蒙古自治区肿瘤医院)药剂科,呼和浩特010020 [2]国药集团川抗制药有限公司,成都611731

出　　处：《中国处方药》2024年第6期88-90,共3页Journal of China Prescription Drug

基　　金：内蒙古自治区卫生健康委2023年首府地区公立医院高水平临床专科建设科技项目(2023SGGZ116-05);2022年内蒙古自治区卫生健康科技计划项目(202202221)。

摘　　要：目的分析1例使用多烯磷脂酰胆碱注射液出现过敏性休克的病例特点及治疗过程,为临床合理用药提供参考。方法报道1例91岁胆囊结石伴急性胆囊炎患者,分析其用药后致过敏性休克原因。结果患者输注完多烯磷脂酰胆碱注射液出现过敏性休克症状,考虑为多烯磷脂酰胆碱注射液导致的不良反应,经治疗后,症状好转。结论多烯磷脂酰胆碱注射液有致过敏性休克的风险,在用药过程中及用药后1h内应密切监测病情变化,一旦出现过敏现象,要考虑药物的可能性,及时停止用药。Objective To analyze the characteristics and treatment process of a case of anaphylactic shock with polyene phosphatidyl choline and provide rational references for clinical prescriptions.Methods The case of an 91-year-old patient with cholecystolithiasis with acute cholecystitis was analyzed,and the cause of anaphylactic shock was investigated.Results The patient developed symptoms of anaphylactic shock after receiving polyene phosphatidylcholine injection.Considering the adverse reactions caused by polyene phosphatidylcholine injection,the symptoms improved after treatment.Conclusion Polyene phosphatidylcholine injection has the risk of causing anaphylactic shock,and should be closely monitored during and within 1 hour after administration.Once allergy occurs,the possibility of the drug should be considered and the drug should be stopped in time.

关 键 词：多烯磷脂酰胆碱 过敏性休克 药物不良反应 病例报告 

分 类 号：R969[医药卫生—药理学]