Elaborate Design of Two Novel Fluorescent Zinc-based Metal-Organic Frameworks for Highly Efficient Tetracycline Antibiotics Detection  

作　　者：TAO He JI Chengshan ZHANG Jian YIN Yuanyuan JIA Wenwen JIANG Xin XU Jie YANG Yulin 

机构地区：[1]MIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage,School of Chemistry and Chemical Engineering,Harbin Institute of Technology,Harbin 150001,P.R.China

出　　处：《Chemical Research in Chinese Universities》2024年第3期499-507,共9页高等学校化学研究（英文版）

基　　金：This work was supported by the National Natural Science Foundation of China(Nos.22072034 and 22001050).

摘　　要：The abuse of tetracycline antibiotics has caused great harm to human health and ecosystems.Developing inexpensive,convenient and sensitive methods for the detection of tetracycline antibiotics is highly desirable.Herein,based on the H_(4)ddp ligand[H_(4)ddp=3-(3,5-dicarboxyphenyl)pyridine-2,6-dicarboxylic acid],two novel zinc-based metal-organic frameworks(MOFs){[Zn_(3)(ddp)_(2)(H_(2)O)_(4)]·3H_(2)O}n(Zn1-ddp)and{[Zn_(3)(ddp)_(2)(H_(2)O)_(4)]·3H_(2)O}n(Zn2-ddp)were successfully designed by delicate structural regulation.Both Zn1-ddp and Zn2-ddp exhibited excellent water and chemical stability and showed excellent fluorescence quenching performance for tetracycline antibiotics.Notably,the more advanced framework structure and better fluorescent performance make Zn1-ddp more sensitive than Zn2-ddp in fluorescent detection with a detection limit of 0.29µmol/L for tetracycline(TC),0.09µmol/L for doxycycline(DOX),0.10µmol/L for minocycline(MIN)and metacycline(MEL),0.19µmol/L for chlortetracycline(CTC),and 0.67µmol/L for oxytetracycline(OTC)among tetracycline antibiotics.The fluorescence quenching mechanism of Zn1-ddp and Zn2-ddp for tetracycline antibiotics detection was deeply investigated.The reasons for the superior detection performance of Zn1-ddp over Zn2-ddp were also analyzed in depth through Fourier transform infrared spectrophotometry(FTIR),X-ray photoelectron spectroscopy(XPS)analysis and framework structure analysis.The developed method opens up a new perspective for antibiotics detection based on zinc-based MOFs.

关 键 词：Water system Metal-organic framework Fluorescent detection Tetracycline antibiotic 

分 类 号：O657.3[理学—分析化学]