超声造影到达时间参数成像对乳腺良恶性疾病诊断价值的研究  

The Study on the Value of Arrival-Time Parametric Imaging Using Contrast-Enhanced Ultrasound in Differentiating Benign and Malignant Breast Lesions

作　　者：于天琦 刘婉君 金壮 蒋南 于馨 张筠 Yu Tianqi;Liu Wanjun;Jin Zhuang;Jiang Nan;Yu Xin;Zhang Yun(Jinzhou Medical University Northern Theater General Hospital Postgraduate Training Base,Shenyang 110016,China;Department of Electric Diagnosis,The Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110000,China;Department of Ultrasound Diagnosis,The General Hospital of Northern Theater Command,Shenyang 110016,China)

机构地区：[1]锦州医科大学北部战区总医院研究生培养基地,沈阳市110016 [2]辽宁中医药大学附属第二医院电检科,沈阳市110000 [3]北部战区总医院超声诊断科,沈阳市110016

出　　处：《中国超声医学杂志》2024年第6期646-648,共3页Chinese Journal of Ultrasound in Medicine

基　　金：沈阳市科学技术计划(No.20-205-4-058)。

摘　　要：目的 评价超声造影到达时间参数成像(At-PI)在鉴别乳腺良恶性病变中的价值。方法 选取有明确病理结果的64个病变。定性分析病变的灌注模式、颜色分布、灌注缺损和缺损边界,定量计算At-PI与常规超声图像上病变的最大长径比(MLA/U)、最大厚径比(MTA/U)、面积比(SA/U)和造影剂到达病变最早与最晚时间差的绝对值。分析定量参数评估乳腺良恶性病变的受试者工作特征曲线下面积。结果 At-PI相较于超声造影具有更好的操作者间一致性。灌注缺损、颜色分布、MLA/U、MTA/U和SA/U在乳腺良恶性病变间有显著差异。结论 At-PI有助于乳腺良恶性病变的鉴别诊断且一致性优于超声造影。Objective To evaluate the value of arrival-time parametric imaging(At-PI)in the differentiation of benign and malignant breast lesions.Methods Sixty-four lesions with pathological results were selected.Perfusion patterns,color spatial distribution for lesions,the perfusion defect,and defect boundary were analyzed qualitatively.The maximal length-diameter ratio of the lesion in At-PI and ultrasound images(UI,MLA u),maximal thickness-diameter ratio of the lesion in At-PI and UI(MTx/u),area ratio of the lesion in At-PI and UI(Sx u)and earliest-final arrival time difference(△T)were calculated quantitatively.The interobserver reproducibility for contrast-enhanced ul-trasound(CEUS)and At-PI was evaluated.The area under receiver operating characteristic curve were calculated for MLA/u,MTx/u,Sa/u,and△T.Results Good interobserver reproducibility for At-PI was identified.In At-PI,there was statistically significant difference in color spatial distribution for lesions,the perfusion defect,MLA/U,MTa/u,and Sa u between benign and malignant breast lesions.Conclusions At-Pl is helpful in distinguishing benign from ma-lignant breast lesions,and has better interobserver reproducibility than CEUS.

关 键 词：超声造影 到达时间参数成像 乳腺良恶性病变 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]