口服甘露醇助显剂超声在小肠黑斑息肉病诊治中的应用价值  

Clinical Value of Oral Mannitol Ultrasonography in the Diagnosis and Treatment of Small Intestine Peutz-Jeghers Syndrome

作　　者：李学荣 张龙方 王洋 梁晓玉 范校周 刘禧 姚克纯 Li Xuerong;Zhang Longfang;Wang Yang;Liang Xiaoyu;Fan Xiaozhou;Liu Xi;Yao Kechun(Graduate School of Hebei North University,Zhangjiakou,Hebei 075000,China;Air Force Medical Center,Air Force Medical University,Beijing 100142,China)

机构地区：[1]河北北方学院研究生院,河北省张家口市075000 [2]空军军医大学空军特色医学中心,北京市100142

出　　处：《中国超声医学杂志》2024年第6期675-678,共4页Chinese Journal of Ultrasound in Medicine

基　　金：2022空军特色医学中心创新项目(No.2022KT15)。

摘　　要：目的 探讨清洁肠道后常规超声及口服甘露醇助显剂超声在小肠黑斑息肉病(PSP)诊治中的应用价值,为该疾病诊断、治疗提供影像学依据。方法 采用常规超声和口服甘露醇助显剂充盈小肠后超声循序追踪扫查各组小肠,以小肠镜所见或术后病理为金标准,对两种方法检出PSP息肉的准确度进行统计分析。结果 54例患者均有典型的口唇、四肢末端黑斑分布。经内镜及病理证实均为PSP息肉,共计326枚息肉。其中常规超声检出214枚息肉,口服甘露醇助显剂超声共检出息肉277枚,口服甘露醇助显剂超声对位于十二指肠和空、回肠内的PSP息肉检出率显著高于常规超声检查,<10 mm、10~30 mm PSP息肉检出率也显著高于常规超声,差异均有统计学意义(P<0.05)。结论 口服甘露醇助显剂超声检查是一种简便易行的检查方法,对于PSP息肉筛查、定位和随访具有较高的应用价值和可行性。Objective To explore the application value of conventional ultrasound and oral mannitol ultrasound in the diagnosis and treatment of small intestinal pigment spot polyposis(PSP),and to provide imaging basis for the di-agnosis and treatment of this disease.Methods Conventional ultrasound and oral mannitol were used to fill the small intestine and then ultrasound was used to track and scan the-small intestine in each group.The accuracy of the two methods in detecting PSP polyps was analyzed using enteroscopy or postoperative pathology as the gold standard.Re-sults All 54 patients had typical distribution of black spots on the lips and extremities.PSP polyps were confirmed by endoscopy and pathology,with a total of 326 polyps.Among them,214 polyps were detected by conventional ultra-sound,and 277 polyps were detected by oral mannitol contrast-enhanced ultrasound.The detection rate of PSP polyps in duodenum,jejunum and ileum by oral mannitol contrast-enhanced ultrasound was significantly higher than that by conventional ultrasound.The detection rate of PSP polyps<10 mm and 10~30 mm was also significantly higher than that of conventional ultrasound,and the differences were statistically significant(P<0.05).Conclusions Oral man-nitol contrast-enhanced ultrasonography is a simple and feasible examination method,which has high application value and feasibility for PSP polyp screening,localization and follow-up.

关 键 词：黑斑息肉病 小肠 息肉 超声检查 

分 类 号：R445.1[医药卫生—影像医学与核医学] R57[医药卫生—诊断学]