2种自拟胶囊改善黄褐斑的人体试食研究  

Human Experimental Study on Improvement of Melasma by Two Kinds of Self-designed Capsules

作　　者：李文静 杨健峰 王梓懿 何蕊 李信心 于洋 苏学峰 LI Wen-jing;YANG Jian-feng;WANG Zi-yi;HE Rui;LI Xin-xin;YU Yang;SU Xue-feng(School of Chemical Engineering,Shaanxi Key Laboratory of Degradable Biomedical Materials,Shaanxi R&D Center of Biomaterials and Fermentation Engineering,Northwest University,Xi’an 710069,China;Xi’an Central Hospital,Xi’an 710004,China)

机构地区：[1]西北大学化工学院,陕西省可降解生物医用材料重点实验室,陕西省生物材料与发酵工程技术研究中心,陕西西安710069 [2]西安市中心医院,陕西西安710004

出　　处：《食品与药品》2024年第3期256-260,共5页Food and Drug

摘　　要：目的观察2种自拟胶囊改善黄褐斑的作用。方法将162例黄褐斑患者随机分为对照组(n=54)、研究组1(n=54,后期2例脱失筛除)和研究组2(n=54),脱失率1.23%。对照组以维生素C和维生素E联合予以治疗;研究组1以自拟组方1(桃仁、茯苓、当归)予以治疗;研究组2以自拟组方2(红花、桃仁、茯苓、当归)予以治疗。结果对照组、研究组1和研究组2的改善黄褐斑的有效率依次为35.19%、55.77%和66.67%,两个研究组的有效率与对照组比较均具有统计学意义(P<0.05,P<0.01),且研究组2的效果更好。结论两种自拟胶囊均有助于改善黄褐斑。Objective To observe the effect of two self-designed capsules on improving melasma.Methods One hundred and sixty-two patients with melasma were randomly divided into control group(n=54),study group 1(n=54,with 2 cases of late loss of screening)and study group 2(n=54),with a loss rate of 1.23%.The control group was treated with vitamin C and vitamin E.Study group 1 was treated with self-made formula 1(Persicae Semen,Poria and Angelicae Sinensis Radix).Study group 2 was treated with self-made formula 2(Carthami Flos,Semen Persicae,Poria and Angelicae Sinensis Radix).Results The improvement rates of the control group,study group 1 and study group 2 were 35.19%,55.77%and 66.67%,respectively.The improvement rates of the two study groups were statistically significant compared with the control group(P<0.05,P<0.01).The improvement effect of study group 2 was better,indicating that Carthami Flos had the effect of removing melasma.Conclusion Both self-designed capsules helps to improve melasma.

关 键 词：红花 桃仁 当归 茯苓 黄褐斑 

分 类 号：R758.42[医药卫生—皮肤病学与性病学]