Evidence-practice gap analysis in the role of tick in brucellosis transmission: a scoping review  

作　　者：Rui Ma Chunfu Li Ai Gao Na Jiang Xinyu Feng Jian Li Wei Hu 

机构地区：[1]不详

出　　处：《Infectious Diseases of Poverty》2024年第1期92-92,共1页贫困所致传染病（英文）

摘　　要：Background Brucellosis is a zoonotic affiction instigated by bacteria belonging to the genus Brucella and is charac-terized by a diverse range of pervasiveness,multiple transmission routes,and serious hazards.It is imperative to amal-gamate the current knowledge and identify gaps pertaining to the role of ticks in brucellosis transmission.Methods We systematically searched China National Knowledge Infrastructure(CNKi),WanFang,Google Scholar,and PubMed on the topic published until April 23,2022.The procedure was performed in accordance with the Sys-tematic Reviews and Meta-Analyses extension for Scoping Reviews(PRISMA-ScR)guidelines.The selected articles were categorized across three major topic areas,and the potential data was extracted to describe evidence-practice gaps by two reviewers.Results The search identifed 83 eligible studies for the final analyses.The results highlighted the potential capacity of ticks in brucellosis transmission as evidenced by the detection of Brucella in 16 different tick species.The pooled overall prevalence of Brucella in ticks was 33.87%(range:0.00-87.80%).The review also revealed the capability of Bru-cella to circulate in parasitic ticks'different developmental stages,thus posing a potential threat to animal and human health.Empirical evidence from in vitro rodent infection experiments has revealed that ticks possess the capability to transmit Brucella to uninfected animals(range:45.00-80.00%).Moreover,significant epidemiological associations have been found between the occurrence of brucellosis in animals and tick control in rangelands,which further suggests that ticks may serve as potential vectors for brucellosis transmission in ruminants.Notably,a mere three cases of human brucellosis resulting from potential tick bites were identified in search of global clinical case reports from 1963to 2019.Conclusions It is imperative to improve the techniques used to identify Brucella in ticks,particularly by developing a novel,efficient,precise approach that can be applied in a field

关 键 词：TICK BRUCELLA Detection Human infection Risk evaluation 

分 类 号：R516.7[医药卫生—内科学] R181.3[医药卫生—临床医学]