中医药治疗艾滋病的进展  

Progress in AIDS Treatment with Traditional Chinese Medicine

作　　者：杨欣怡 苏琛[1] 刘晶晶[1] 张春梅[1] 唐丽燕[1] 李东晓[1] 彭鑫 YANG Xinyi;SU Chen;LIU Jingjing;ZHANG Chunmei;TANG liyan;LI dongxiao;PENG Xin(Sichuan Academy of Chinese Medicine Sciences,Chengdu 610041)

机构地区：[1]四川省中医药科学院,成都610041

出　　处：《中药药理与临床》2024年第4期4-8,26,共6页Pharmacology and Clinics of Chinese Materia Medica

基　　金：四川省科技厅重点研发项目(编号:2019YFS0023);2023四川省省级科研院所基本科研业务费项目(编号:2023JDKY0027)。

摘　　要：中医药介入艾滋病研究已三十余年,在稳定或提高免疫能力,治疗药物不良反应,延缓发病时间及治疗机会性感染等方面发挥了积极作用。而在抗反转录病毒治疗广泛使用的当下,如何找准定位、确定目的是今后开展中医药治疗艾滋病研究需要解决的关键问题。因此,本文对近年来中医药辨治艾滋病的相关研究进行了总结,为下一步深化研究提供参考。目前关于中医药治疗艾滋病相关研究包括了艾滋病及其并发症的证型、体质、药物制剂研究;临床治疗重难点问题有免疫重建不良、机会性感染、药物不良反应和合并疾病等。今后当发挥中医药在抗病毒治疗失败、免疫重建不良及缓解药物不良反应等方面的特长优势,集中力量突破关键问题,多学科合作,加强基础研究,提供高级别循证证据,并结合高新技术手段进行研究,解决艾滋病相关疑难问题。Traditional Chinese medicine(TCM)has treated acquired immune deficiency syndrome(AIDS)for more than 30 years and has played a positive role in stabilizing or improving the immune capacity,alleviating adverse reactions,retarding the onset of AIDS,and treating opportunistic infections.Currently,antiretroviral therapy is widely used,and determining the treatment direction and purpose is a key point that needs to be solved in future research on the treatment of AIDS with TCM.Therefore,this article summarized the relevant research on the differentiation and treatment of AIDS with TCM in recent years and provided a reference for in-depth research.At present,the related research on the treatment of AIDS with TCM includes the syndrome types,constitutions,and drug preparations related to AIDS and its complications;key and difficult clinical issues are poor immune reconstitution,opportunistic infections,adverse drug reactions,and complications.In the future,it is necessary to take advantage of TCM to facilitate antiviral treatment,improve poor immune reconstitution,and alleviate adverse drug reactions and focus on solving key problems,encouraging multi-disciplinary cooperation,strengthening basic research,providing high-level evidence-based evidence,and adopting high-tech methods,so as to solve difficult problems related to AIDS.

关 键 词：艾滋病 获得性免疫缺陷综合征 中医药 免疫重建不良 机会性感染 药物不良反应 

分 类 号：R259[医药卫生—中西医结合]