基于数据挖掘探究中医古籍中腰痹膏摩处方药物选用规律  

Exploration of Medication Selection Rules of Tuina with Ointment Prescription for Lumbar Bi Disease in Chinese Medicine Ancient Books Based on Data Mining

作　　者：李飞 董航 高天蕾 杨留映 王爽 张星贺 LI Fei;DONG Hang;GAO Tianlei;YANG Liuying;WANG Shuang;ZHANG Xinghe(The Second Clinical Medical College of Yunnan University of Chinese Medicine,Kunming Yunnan 650500,China)

机构地区：[1]云南中医药大学第二临床医学院,云南昆明650500

出　　处：《新中医》2024年第10期7-13,共7页New Chinese Medicine

基　　金：云南省基础研究计划中医联合专项面上项目(202101AZ070001-189)。

摘　　要：目的:通过数据挖掘技术分析中医古籍中治疗腰痹的膏摩处方的药物选用规律。方法:查阅并分析中医古籍中用于治疗腰痹的膏摩处方,提取古籍出处、方名、处方药物,采用SATI软件分析处方药物及其四气、五味、归经的频次、支持度,采用UCINET、NetDraw软件分析药物的中心度。结果:通过查阅37本含有腰痹膏摩方的古籍,共检索出81首治疗腰痹的膏摩处方,涉及217味中药,药物使用总频次为958次。《圣济总录》《普济方》《太平圣惠方》是记载膏摩处方较多的古籍。方名“摩腰膏”出现次数最多(方名相同,但部分药物不同),频次为9次,其次是摩腰丹,频次为7次。附子使用频次最多,达37次,其余使用频次≥20次的药物,按使用频次由高到低依次是花椒、当归、吴茱萸、干姜、川芎、丁香、朱砂、雄黄、白芷、肉桂、生姜、麝香、细辛。醋、猪脂是使用最多的制膏辅料。选用的药物以温、热性药为主,其次是寒、平性药和凉性药;选用的药物多为辛味药,其次是苦、甘味药;选用的药物多为归肝、脾经的药物。结论:采用膏摩疗法治疗腰痹应以温、通、补法为主,重视肝脾、肝肾同治。利用现代技术提取中药有效成分,结合最新的制膏工艺,可制作出性质更稳定、功效更显著、更适用于临床的膏摩剂型,是膏摩疗法发展的重要部分。Objective:To analyze the medication selection rules of tuina with ointment prescription for lumbar bi disease in Chinese medicine ancient books based on data mining.Methods:The ointment prescriptions for tuina in the treatment of lumbar bi disease in ancient books of Chinese medicine were consulted and analyzed.The source,prescription name,and the medicinals involved were extracted.The SATI software was used to analyze the medicinals in the prescriptions,and the frequency and support of their four qi,five flavors,and meridian tropism.The centrality of medicinals was analyzed by UCINET and NetDraw software.Results:Through searching 37 ancient books containing tuina with ointment for lumbar paralysis,a total of 81 ointment prescriptions for tuina in the treatment of lumbar bi disease were retrieved,involving 217 Chinese medicinals,and the total frequency of medicinals use was 958 times.Sheng Ji Zong Lu(Comprehensive Recording of Divine Assistance),Pu Ji Fang(Formulas for Universal Relief),and Tai Ping Sheng Hui Fang(Formulas from Benevolent Sages Compiled during the Taiping Era)are ancient books that record many ointment prescriptions for tuina.The prescription name"Moyao Gao"(Moyao Ointment)appeared the most(these prescriptions share the same name,but some medicinals involved are different),with a frequency of 9 times,followed by Moyao Dan(Moyao Pellets)whose frequency is 7 times.Aconiti Lateralis Radix Praeparata has the highest frequency of 37 times;among other medicinals with a frequency that is equal to or more than 20 times,their order of usage frequency from high to low is as follows:Zanthoxyli Pericarpium,Angelicae Sinensis Radix,Euodiae Fructus,Zingiberis Rhizoma,Chuanxiong Rhizoma,Caryophylli Flos,Cinnabaris,Realgar,Angelicae Dahuricae Radix,Cinnamomi Cortex,Zingiberis Rhizoma Recens,Moschus,and Asari Radix et Rhizoma.Vinegar and lard are the most used subsidiary materials for ointment-making.The natures of selected medicinals are mainly warm and heat,followed by cold,neutral and cool.The flavors of selec

关 键 词：腰痹 膏摩疗法 数据挖掘 中医古籍 用药规律 

分 类 号：R274.34[医药卫生—中医骨伤科学]