1990至2019年中国职业性肺癌疾病负担分析  

An analysis of disease burden of occupational lung cancer in China from 1990 to 2019

作　　者：马宏境[1] 黄少祥[1] 曾妮[1] Ma Hongjing;Huang Shaoxiang;Zeng Ni(Department of Respiratory,Tianjin Fifth Central Hospital,Tianjin 300450,China)

机构地区：[1]天津市第五中心医院呼吸科,天津300450

出　　处：《中华劳动卫生职业病杂志》2024年第5期355-359,共5页Chinese Journal of Industrial Hygiene and Occupational Diseases

摘　　要：目的分析中国1990至2019年职业性肺癌的死亡率和伤残调整寿命年等疾病负担的变化。方法于2022年6月,采用全球疾病负担数据库(GBD)中职业性肺癌数据,采用死亡率、伤残调整寿命年(DALYs)及其年龄标化率比较分析,应用Joinpoint Regression Program软件分析年度变化百分比(APC)和平均年度百分比变化率(AAPC)。结果1990年至2019年中国职业性肺癌年龄标化死亡率由2.41/10万增至3.14/10万,DALYs由58万人年增至150.99万人年,标化DALYs率由63.03/10万增至71.65/10万。年龄标化死亡率和DALYs率在2011至2016年下降,2016至2019年增高趋势低于2011年之前的阶段,但差异无统计学意义(t=-0.10、0.30,P=0.961、0.735)。死亡率、标化死亡率、DALYs率和标化DALYs率的APCC值分别为3.28、0.92、2.64和0.44,趋势差异有统计学意义(t=28.65、9.47、23.07、4.11,P<0.001)。结论1990至2019年我国职业性肺癌疾病负担总体呈上升趋势,应对高危人群进行肺癌筛查,以实现早诊早治。ObjectiveTo analyze the trend of disease burden,including mortality and disability-adjusted life years(DALYs),of occupational lung cancer in China from 1990 to 2019.MethodsIn June 2022,the data of occupational lung cancer was obtained from Global Burden of Disease Study 2019(GBD).Excel summarized the data,and the mortality rate,DALYs and age-normalized rate were analyzed.Applying Joinpoint Regression Program software annual Percentage Change(APC)and Average Annual Percentage Change Rate(AAPC).ResultsAge-standardized mortality rates ranged from 2.41 in 1990 to 3.14 per 100000 in 2019,with gender differences and a positive correlation with age.DALYs increased from 580,000 person-years in 1990 to 1509900 person-years in 2019.The rate of standardized DALYs increased from 63.03 per 100000 in 1990 to 71.65 per 100000 in 2019.According to the annual percentage change(APC)analysis by Joinpoint Regression Program software,the age-normalized mortality and DALY rates decreased from 2011 to 2016,and the increasing trend from 2016 to 2019 was significantly lower than that before 2011.And the increase at this stage was not statistically significant.The APCC values of mortality rate,standardized mortality rate,DALYs rate and changed DALYs rate were 3.28,0.92,2.64 and 0.44,respectively,and the trend differences were statistically significant.ConclusionThe disease burden of occupational lung cancer is increasing from 1990 to 2019.Lung cancer screening should be carried out among high-risk populations to achieve early diagnosis and treatment.

关 键 词：职业性肺癌 疾病负担 死亡率 伤残调整寿命年 

分 类 号：R135[医药卫生—劳动卫生] R734.2[医药卫生—公共卫生与预防医学]