非那雄胺联合经尿道前列腺等离子体双极电切术对良性前列腺增生患者术后疼痛程度、尿动力学的影响  

Effects of finasteride combined with transurethral plasmakinetic resection of the prostate on postoperative pain degree and urodynamics in patients with benign prostate hyperplasia

作　　者：赵良伟 王勇伟[1] 钱乐 杨浩[1] 姚丽娟[1] 许增宝[1] 张胜景 ZHAO Liangwei;WANG Yongwei;QIAN Le;YANG Hao;YAO Lijuan;XU Zengbao;ZHANG Shengjing(Department of Urology,Huzhou Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical University,Huzhou 313000,Zhejiang,China;Department of Urology,the Second Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310005,Zhejiang,China)

机构地区：[1]浙江中医药大学附属湖州市中医院泌尿外科,浙江湖州313000 [2]浙江中医药大学附属第二医院泌尿外科,杭州310005

出　　处：《中国性科学》2024年第6期27-30,共4页Chinese Journal of Human Sexuality

基　　金：浙江中医药大学校级科研项目(2021FSYYZY36)。

摘　　要：目的探讨非那雄胺联合经尿道前列腺等离子体双极电切术对良性前列腺增生患者术后疼痛程度、尿动力学的影响。方法选取2021年1月至2022年12月浙江中医药大学附属湖州市中医院及浙江中医药大学附属第二医院收治的100例良性前列腺增生患者作为研究对象。随机分为对照组(采用经尿道前列腺等离子体双极电切术)和观察组(采用经尿道前列腺等离子体双极电切术联合非那雄胺),各50例。比较两组的一般手术指标、术后疼痛程度、尿动力学指标、术后并发症发生率。结果观察组手术时间、尿管拔除时间、住院时间比对照组短,术中出血量比对照组少,差异具有统计学意义(P<0.05);术后,观察组疼痛程度优于对照组,差异具有统计学意义(P<0.05);观察组并发症发生率低于对照组,但差异无统计学意义(P>0.05);术后6个月,两组残余尿量(PVR)水平下降,且观察组低于对照组,两组最大尿流率(Qmax)、膀胱顺应性(BC)水平升高,且观察组高于对照组,差异具有统计学意义(P<0.05)。结论非那雄胺联合经尿道前列腺等离子体双极电切术治疗良性前列腺增生的临床效果好,可缩短手术时间、尿管拔除时间、住院时间,减少术中出血量,且可有效减轻患者术后疼痛,减少PVR,增加Qmax及BC。Objective To explore the effects of finasteride combined with transurethral plasmakinetic resection of the prostate on pain degree and urodynamics in patients with benign prostate hyperplasia(BPH).Methods A total of 100 patients with BPH admitted to Huzhou Traditional Chinese Medicine Hospital Affiliated to Zhejiang Chinese Medical University and the Second Affiliated Hospital of Zhejiang Chinese Medical University from Jamuary 2021 to December 2022 were selected as the study objects.They were randomly divided into control group(using transurethral plasmakinetic resection of the prostate)and observation group(using transurethral plasmakinetic resection of the prostate combined with finasteride),with 50 cases in each group.The general surgical indexes,postoperative pain degree,urodynamic indicators and postoperative complication incidence were compared between the two groups.Results The operation duration,urinary tube removal time and hospital stay in the observation group were shorter than those in the control group,and the intraoperative blood loss was less than that in the control group,with the statistically significant differences(P<0.05).After operation,the pain degree of the observation group was better than that of the control group,and the diference was statistically significant(P<0.05).The incidence of complications in the observation group was lower than that in the control group,but the difference was not statistically significant(P>0.05).After 6 months of operation,postvoid residual(PVR)level decreased in both groups,and the value in the observation group was lower than that in the control group,the maximum urinary flow mate(Qmax)and bladder compliance(BC)levels increased in both goups,and the value in the observation group was higher than that in the control group,with statistically significant differences(P<0.05).Conclusions Finasteride combined with transurethral plasmakinetic resection of the prostate have good clinical effects on treating BPH,with shorter operative duration,shorter urinary tube r

关 键 词：非那雄胺 经尿道前列腺等离子体双极电切术 良性前列腺增生 疼痛程度 尿动力学 

分 类 号：R697[医药卫生—泌尿科学]