慢性冠状动脉疾病经皮冠状动脉介入术后CatLet评分与支架内再狭窄的关联性研究  

Study on correlation between CatLet score and in-stent restenosis after percutaneous coronary intervention in patients with chronic coronary artery disease

作　　者：汪娟 张明超 徐明星 鲁大胜 杨凌飞 Wang Juan;Zhang Mingchao;Xu Mingxing;Lu Dasheng;Yang Lingfei(Department of Cardiology,the Second Affiliated Hospital of Wannan Medical College,Wuhu,Anhui 241000,China;Department of Geriatrics,Hefei First People's Hospital,Hefei,Anhui 230000,China)

机构地区：[1]皖南医学院第二附属医院心内科,安徽芜湖241000 [2]合肥市第一人民医院老年科,安徽合肥230000

出　　处：《齐齐哈尔医学院学报》2024年第12期1113-1119,共7页Journal of Qiqihar Medical University

基　　金：国自然青年项目基金(81800445);校级自然科学基金(WK2023ZQNZ68)。

摘　　要：目的探究慢性冠状动脉疾病患者在进行冠状动脉介入(PCI)术后,CatLet评分与冠状动脉支架内再狭窄(ISR)之间的关系。方法选择2020年1月—2021年6月本院确诊为慢性冠心病并接受冠状动脉支架植入术的260例患者作为研究对象,进行为期2年的随访,其中有200例完成了第二次冠脉造影检查以评估ISR的发生情况,最终有164例符合纳入和排除标准并参与统计学分析。研究收集了第一次冠脉造影时的基线数据,其中CatLet评分通过在线网站计算获得。结果本研究共164例患者(女48例,男116例),平均年龄(66.19±10.54)岁,其中26例患者发生ISR(ISR组),其发生率为15.85%,另外138例患者作为非ISR组。两组患者在性别、年龄、糖尿病、高血压、支架直径、支架长度方面并无明显差异,通过Logistic逐步回归分析发现,CatLet评分较高的患者患有慢性冠心病ISR的风险较大(OR=1.03,95%CI=1.00~1.05,P=0.03)。结论对于患有慢性冠心病患者而言,CatLet评分可以作为预测冠脉介入术后ISR的一个独立危险因素,可以作为预测该疾病的指标之一。Objective To investigate the correlation between CatLet score and coronary in-stent restenosis(ISR)following percutaneous coronary intervention in patients with chronic coronary artery disease.Methods A total of 260 patients who were diagnosed with chronic coronary artery disease and underwent coronary stenting implantation in the Second Affiliated Hospital of Wannan Medical College were consecutively enrolled from January 2020 to June 2021,and the patients were followed up for 2 years.Of these,200 patients completed a second coronary angiography to evaluate the presence of ISR,and ultimately,164 of these patients who met the inclusion and exclusion criteria were included for statistical analysis.Baseline data were collected at the time of the first coronary angiography,where the CatLet score was calculated via an online website.Results The study included a total of 164 patients(48 women and 116 men)with a mean age of 66.19±10.54 years old.Among them,26 patients had ISR(ISR group),and the incidence was 15.85%,and the other 138 patients were classified as non-ISR group.There was no significant difference in gender,age,diabetes,hypertension,stent diameter and stent length between the two groups.Logistic stepwise regression analysis showed that patients with higher CatLet score had a higher risk of ISR in chronic coronary heart disease(OR=1.03,95%CI=1.00~1.05,P=0.03).Conclusions For patients with chronic coronary heart disease,CatLet score can be used as an independent risk factor to predict ISR after coronary intervention,and can be used as one of the indicators to predict the disease.

关 键 词：支架内再狭窄 CatLet评分 慢性冠脉疾病 

分 类 号：R541[医药卫生—心血管疾病]