双面不对称补片在腹壁组织缺损修复中的应用  

Application of double-sided asymmetric composite meshes in abdominal wall defect repair

作　　者：欧阳阳 于洋 熊闻轩 王辉[1] 黄榕康[1] Yang Ouyang;Yang Yu;Wenxuan Xiong;Hui Wang;Rongkang Huang(Department of General Surgery(Colorectal Surgery),The Sixth Affiliated Hospital,Sun Yat-sen University,Guangzhou 510655,China;Zhongshan School of Medicine,Sun Yat-sen University,Guangzhou 510006,China)

机构地区：[1]中山大学附属第六医院普通外科(结直肠外科),广州510655 [2]中山大学中山医学院,广州510006

出　　处：《中华疝和腹壁外科杂志（电子版）》2024年第2期125-131,共7页Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition)

基　　金：国家自然科学基金(22271320);广东省基础与应用基础研究基金(2021A1515110856);北京白求恩公益基金会(10012)。

摘　　要：无张力补片修补术是腹壁缺损的首选治疗方式。然而,与单纯的腹股沟疝等腹壁缺损相比,创伤、腹壁肠造口或肿瘤切除手术等因素导致的复杂型腹壁缺损近年来日益增多,对修补材料的性能提出了更高的要求。现有商用补片在临床实践中仍面临许多亟需解决的瓶颈问题,如感染、腹腔内粘连、愈合缓慢、补片移位等,难以实现缺损组织的高效修复。本文就现有商业补片和新型双面不对称高分子补片材料进行总结和阐述并对软组织修复材料领域可能面临的挑战、机遇以及未来的研究方向进行了展望。Tension-free mesh repair is the preferred method for treating abdominal wall defects.However,compared to simple abdominal wall defects such as inguinal hernias,complex abdominal wall defects caused by trauma,abdominal wall stoma,or tumor resection surgeries have become increasingly prevalent in recent years,and higher requirements are placed on the performance of repair materials.Commercial meshes still face many critical challenges in clinical practice,such as infections,intra-abdominal adhesions,slow healing,and mesh displacement,making it difficult to achieve efficient repair of defective tissues.This paper presents an overview of current commercial meshes and novel double-sided asymmetric composite polymer meshes,and provides a perspective on the potential challenges,opportunities,and future research directions in the field of soft tissue repair materials.

关 键 词：腹壁缺损 补片 双面不对称 复合材料 

分 类 号：R656.21[医药卫生—外科学]